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Xuanfei Baidu Decoction suppresses complement overactivation and ameliorates IgG immune complex-induced acute lung injury by inhibiting JAK2/STAT3/SOCS3 and NF-κB signaling pathway

BACKGROUND: The significant clinical efficacy of Xuanfei Baidu Decoction (XFBD) is proven in the treatment of patients with coronavirus disease 2019 (COVID-19) in China. However, the mechanisms of XFBD against acute lung injury (ALI) are still poorly understood. METHODS: In vivo, the mouse model of...

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Detalles Bibliográficos
Autores principales: Li, Caixia, Li, Yuhong, Zhang, Han, Zhuo, Yuzhen, Zhang, Lanqiu, Yang, Lei, Gao, Qiaoying, Tu, Zhengwei, Shao, Rui, Wang, Yu, Zhang, Junhua, Cui, Lihua, Zhang, Shukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier GmbH. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678227/
https://www.ncbi.nlm.nih.gov/pubmed/36610119
http://dx.doi.org/10.1016/j.phymed.2022.154551