A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol

INTRODUCTION: Drug development for neurodegenerative diseases such as Friedreich’s ataxia (FRDA) is limited by a lack of validated, sensitive biomarkers of pharmacodynamic response in affected tissue and disease progression. Studies employing neuroimaging measures to track FRDA have thus far been li...

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Detalles Bibliográficos
Autores principales: Georgiou-Karistianis, Nellie, Corben, Louise A., Reetz, Kathrin, Adanyeguh, Isaac M., Corti, Manuela, Deelchand, Dinesh K., Delatycki, Martin B., Dogan, Imis, Evans, Rebecca, Farmer, Jennifer, França, Marcondes C., Gaetz, William, Harding, Ian H., Harris, Karen S., Hersch, Steven, Joules, Richard, Joers, James J., Krishnan, Michelle L., Lax, Michelle, Lock, Eric F., Lynch, David, Mareci, Thomas, Muthuhetti Gamage, Sahan, Pandolfo, Massimo, Papoutsi, Marina, Rezende, Thiago J. R., Roberts, Timothy P. L., Rosenberg, Jens T., Romanzetti, Sandro, Schulz, Jörg B., Schilling, Traci, Schwarz, Adam J., Subramony, Sub, Yao, Bert, Zicha, Stephen, Lenglet, Christophe, Henry, Pierre-Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678384/
https://www.ncbi.nlm.nih.gov/pubmed/36410013
http://dx.doi.org/10.1371/journal.pone.0269649

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