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Calmangafodipir for Prevention of Oxaliplatin-Induced Peripheral Neuropathy: Two Placebo-Controlled, Randomized Phase 3 Studies (POLAR-A/POLAR-M)
BACKGROUND: Calmangafodipir (CaM, PledOx) demonstrated efficacy in preventing patient-reported chemotherapy-induced peripheral neuropathy (CIPN) in a randomized phase 2 study in patients with metastatic colorectal cancer. The Preventive Treatment of OxaLiplatin Induced peripherAl neuRopathy (POLAR)...
Autores principales: | Pfeiffer, Per, Lustberg, Maryam, Näsström, Jacques, Carlsson, Stefan, Persson, Anders, Nagahama, Fumiko, Cavaletti, Guido, Glimelius, Bengt, Muro, Kei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678401/ https://www.ncbi.nlm.nih.gov/pubmed/36308441 http://dx.doi.org/10.1093/jncics/pkac075 |
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