Cargando…

Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net

One of the most prevalent malignant bone tumors is osteosarcoma. The diagnosis and treatment cycle are long and the prognosis is poor. It takes a lot of time to manually identify osteosarcoma from osteosarcoma magnetic resonance imaging (MRI). Medical image processing technology has greatly alleviat...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Feng, Zhu, Jun, Lv, Baolong, Yang, Lei, Sun, Wenyan, Dai, Zhehao, Gou, Fangfang, Wu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678467/
https://www.ncbi.nlm.nih.gov/pubmed/36419505
http://dx.doi.org/10.1155/2022/9990092
_version_ 1784833991463927808
author Liu, Feng
Zhu, Jun
Lv, Baolong
Yang, Lei
Sun, Wenyan
Dai, Zhehao
Gou, Fangfang
Wu, Jia
author_facet Liu, Feng
Zhu, Jun
Lv, Baolong
Yang, Lei
Sun, Wenyan
Dai, Zhehao
Gou, Fangfang
Wu, Jia
author_sort Liu, Feng
collection PubMed
description One of the most prevalent malignant bone tumors is osteosarcoma. The diagnosis and treatment cycle are long and the prognosis is poor. It takes a lot of time to manually identify osteosarcoma from osteosarcoma magnetic resonance imaging (MRI). Medical image processing technology has greatly alleviated the problems faced by medical diagnoses. However, MRI images of osteosarcoma are characterized by high noise and blurred edges. The complex features increase the difficulty of lesion area identification. Therefore, this study proposes an osteosarcoma MRI image segmentation method (OSTransnet) based on Transformer and U-net. This technique primarily addresses the issues of fuzzy tumor edge segmentation and overfitting brought on by data noise. First, we optimize the dataset by changing the precise spatial distribution of noise and the data-increment image rotation process. The tumor is then segmented based on the model of U-Net and Transformer with edge improvement. It compensates for the limitations of U-semantic Net by using channel-based transformers. Finally, we also add an edge enhancement module (BAB) and a combined loss function to improve the performance of edge segmentation. The method's accuracy and stability are demonstrated by the detection and training results based on more than 4,000 MRI images of osteosarcoma, which also demonstrate how well the method works as an adjunct to clinical diagnosis and treatment.
format Online
Article
Text
id pubmed-9678467
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-96784672022-11-22 Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net Liu, Feng Zhu, Jun Lv, Baolong Yang, Lei Sun, Wenyan Dai, Zhehao Gou, Fangfang Wu, Jia Comput Intell Neurosci Research Article One of the most prevalent malignant bone tumors is osteosarcoma. The diagnosis and treatment cycle are long and the prognosis is poor. It takes a lot of time to manually identify osteosarcoma from osteosarcoma magnetic resonance imaging (MRI). Medical image processing technology has greatly alleviated the problems faced by medical diagnoses. However, MRI images of osteosarcoma are characterized by high noise and blurred edges. The complex features increase the difficulty of lesion area identification. Therefore, this study proposes an osteosarcoma MRI image segmentation method (OSTransnet) based on Transformer and U-net. This technique primarily addresses the issues of fuzzy tumor edge segmentation and overfitting brought on by data noise. First, we optimize the dataset by changing the precise spatial distribution of noise and the data-increment image rotation process. The tumor is then segmented based on the model of U-Net and Transformer with edge improvement. It compensates for the limitations of U-semantic Net by using channel-based transformers. Finally, we also add an edge enhancement module (BAB) and a combined loss function to improve the performance of edge segmentation. The method's accuracy and stability are demonstrated by the detection and training results based on more than 4,000 MRI images of osteosarcoma, which also demonstrate how well the method works as an adjunct to clinical diagnosis and treatment. Hindawi 2022-11-14 /pmc/articles/PMC9678467/ /pubmed/36419505 http://dx.doi.org/10.1155/2022/9990092 Text en Copyright © 2022 Feng Liu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Liu, Feng
Zhu, Jun
Lv, Baolong
Yang, Lei
Sun, Wenyan
Dai, Zhehao
Gou, Fangfang
Wu, Jia
Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net
title Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net
title_full Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net
title_fullStr Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net
title_full_unstemmed Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net
title_short Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net
title_sort auxiliary segmentation method of osteosarcoma mri image based on transformer and u-net
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678467/
https://www.ncbi.nlm.nih.gov/pubmed/36419505
http://dx.doi.org/10.1155/2022/9990092
work_keys_str_mv AT liufeng auxiliarysegmentationmethodofosteosarcomamriimagebasedontransformerandunet
AT zhujun auxiliarysegmentationmethodofosteosarcomamriimagebasedontransformerandunet
AT lvbaolong auxiliarysegmentationmethodofosteosarcomamriimagebasedontransformerandunet
AT yanglei auxiliarysegmentationmethodofosteosarcomamriimagebasedontransformerandunet
AT sunwenyan auxiliarysegmentationmethodofosteosarcomamriimagebasedontransformerandunet
AT daizhehao auxiliarysegmentationmethodofosteosarcomamriimagebasedontransformerandunet
AT goufangfang auxiliarysegmentationmethodofosteosarcomamriimagebasedontransformerandunet
AT wujia auxiliarysegmentationmethodofosteosarcomamriimagebasedontransformerandunet