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Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net
One of the most prevalent malignant bone tumors is osteosarcoma. The diagnosis and treatment cycle are long and the prognosis is poor. It takes a lot of time to manually identify osteosarcoma from osteosarcoma magnetic resonance imaging (MRI). Medical image processing technology has greatly alleviat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678467/ https://www.ncbi.nlm.nih.gov/pubmed/36419505 http://dx.doi.org/10.1155/2022/9990092 |
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author | Liu, Feng Zhu, Jun Lv, Baolong Yang, Lei Sun, Wenyan Dai, Zhehao Gou, Fangfang Wu, Jia |
author_facet | Liu, Feng Zhu, Jun Lv, Baolong Yang, Lei Sun, Wenyan Dai, Zhehao Gou, Fangfang Wu, Jia |
author_sort | Liu, Feng |
collection | PubMed |
description | One of the most prevalent malignant bone tumors is osteosarcoma. The diagnosis and treatment cycle are long and the prognosis is poor. It takes a lot of time to manually identify osteosarcoma from osteosarcoma magnetic resonance imaging (MRI). Medical image processing technology has greatly alleviated the problems faced by medical diagnoses. However, MRI images of osteosarcoma are characterized by high noise and blurred edges. The complex features increase the difficulty of lesion area identification. Therefore, this study proposes an osteosarcoma MRI image segmentation method (OSTransnet) based on Transformer and U-net. This technique primarily addresses the issues of fuzzy tumor edge segmentation and overfitting brought on by data noise. First, we optimize the dataset by changing the precise spatial distribution of noise and the data-increment image rotation process. The tumor is then segmented based on the model of U-Net and Transformer with edge improvement. It compensates for the limitations of U-semantic Net by using channel-based transformers. Finally, we also add an edge enhancement module (BAB) and a combined loss function to improve the performance of edge segmentation. The method's accuracy and stability are demonstrated by the detection and training results based on more than 4,000 MRI images of osteosarcoma, which also demonstrate how well the method works as an adjunct to clinical diagnosis and treatment. |
format | Online Article Text |
id | pubmed-9678467 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-96784672022-11-22 Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net Liu, Feng Zhu, Jun Lv, Baolong Yang, Lei Sun, Wenyan Dai, Zhehao Gou, Fangfang Wu, Jia Comput Intell Neurosci Research Article One of the most prevalent malignant bone tumors is osteosarcoma. The diagnosis and treatment cycle are long and the prognosis is poor. It takes a lot of time to manually identify osteosarcoma from osteosarcoma magnetic resonance imaging (MRI). Medical image processing technology has greatly alleviated the problems faced by medical diagnoses. However, MRI images of osteosarcoma are characterized by high noise and blurred edges. The complex features increase the difficulty of lesion area identification. Therefore, this study proposes an osteosarcoma MRI image segmentation method (OSTransnet) based on Transformer and U-net. This technique primarily addresses the issues of fuzzy tumor edge segmentation and overfitting brought on by data noise. First, we optimize the dataset by changing the precise spatial distribution of noise and the data-increment image rotation process. The tumor is then segmented based on the model of U-Net and Transformer with edge improvement. It compensates for the limitations of U-semantic Net by using channel-based transformers. Finally, we also add an edge enhancement module (BAB) and a combined loss function to improve the performance of edge segmentation. The method's accuracy and stability are demonstrated by the detection and training results based on more than 4,000 MRI images of osteosarcoma, which also demonstrate how well the method works as an adjunct to clinical diagnosis and treatment. Hindawi 2022-11-14 /pmc/articles/PMC9678467/ /pubmed/36419505 http://dx.doi.org/10.1155/2022/9990092 Text en Copyright © 2022 Feng Liu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Liu, Feng Zhu, Jun Lv, Baolong Yang, Lei Sun, Wenyan Dai, Zhehao Gou, Fangfang Wu, Jia Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net |
title | Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net |
title_full | Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net |
title_fullStr | Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net |
title_full_unstemmed | Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net |
title_short | Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net |
title_sort | auxiliary segmentation method of osteosarcoma mri image based on transformer and u-net |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678467/ https://www.ncbi.nlm.nih.gov/pubmed/36419505 http://dx.doi.org/10.1155/2022/9990092 |
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