Cargando…

The ectromelia virus virulence factor C15 facilitates early viral spread by inhibiting NK cell contact

The success of poxviruses as pathogens depends on their antagonism of host responses by multiple immunomodulatory proteins. The largest of these expressed by ectromelia virus (the agent of mousepox) is C15, one member of a well-conserved poxviral family previously shown to inhibit T cell activation....

Descripción completa

Detalles Bibliográficos
Autores principales: Peauroi, Elise M., Carro, Stephen D., Pei, Luxin, Reynoso, Glennys V., Hickman, Heather D., Eisenlohr, Laurence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678732/
https://www.ncbi.nlm.nih.gov/pubmed/36425759
http://dx.doi.org/10.1016/j.isci.2022.105510