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Quantitative landscapes reveal trajectories of cell-state transitions associated with drug resistance in melanoma
Drug resistance and tumor relapse in patients with melanoma is attributed to a combination of genetic and non-genetic mechanisms. Dedifferentiation, a common mechanism of non-genetic resistance in melanoma is characterized by the loss of melanocytic markers. While various molecular attributes of de-...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678737/ https://www.ncbi.nlm.nih.gov/pubmed/36425754 http://dx.doi.org/10.1016/j.isci.2022.105499 |