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The hairpin region of WNT7A is sufficient for binding to the Frizzled7 receptor and to elicit signaling in myogenic cells

Wnt signaling is essential for embryonic development and tissue homeostasis. So far, little is known about the importance and functional relevance of the different regions in WNT proteins including regions in their C-terminus identified as hairpin and linker. However, it was shown that the C-terminu...

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Detalles Bibliográficos
Autores principales: Schmidt, Manuel, Poser, Christine, Janster, Christina, von Maltzahn, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678774/
https://www.ncbi.nlm.nih.gov/pubmed/36420144
http://dx.doi.org/10.1016/j.csbj.2022.10.047

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