Cargando…
The hairpin region of WNT7A is sufficient for binding to the Frizzled7 receptor and to elicit signaling in myogenic cells
Wnt signaling is essential for embryonic development and tissue homeostasis. So far, little is known about the importance and functional relevance of the different regions in WNT proteins including regions in their C-terminus identified as hairpin and linker. However, it was shown that the C-terminu...
Autores principales: | Schmidt, Manuel, Poser, Christine, Janster, Christina, von Maltzahn, Julia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678774/ https://www.ncbi.nlm.nih.gov/pubmed/36420144 http://dx.doi.org/10.1016/j.csbj.2022.10.047 |
Ejemplares similares
-
Wnt7a Counteracts Cancer Cachexia
por: Schmidt, Manuel, et al.
Publicado: (2020) -
Stimulation of Non-canonical NF-κB Through Lymphotoxin-β-Receptor Impairs Myogenic Differentiation and Regeneration of Skeletal Muscle
por: Schmidt, Manuel, et al.
Publicado: (2021) -
Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength
por: Bentzinger, C. Florian, et al.
Publicado: (2014) -
Frizzled 7 and PIP(2) binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling
por: Egea-Jimenez, Antonio Luis, et al.
Publicado: (2016) -
Wnt7a/Fzd7 Signalling Directly Activates the Akt/mTOR Anabolic Growth Pathway in Skeletal Muscle
por: von Maltzahn, Julia, et al.
Publicado: (2011)