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G protein gamma subunit, a hidden master regulator of GPCR signaling

Heterotrimeric G proteins (αβγ subunits) that are activated by G protein-coupled receptors (GPCRs) mediate the biological responses of eukaryotic cells to extracellular signals. The α subunits and the tightly bound βγ subunit complex of G proteins have been extensively studied and shown to control t...

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Detalles Bibliográficos
Autores principales: Kankanamge, Dinesh, Tennakoon, Mithila, Karunarathne, Ajith, Gautam, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678972/
https://www.ncbi.nlm.nih.gov/pubmed/36272647
http://dx.doi.org/10.1016/j.jbc.2022.102618