Baat Gene Knockout Alters Post-Natal Development, the Gut Microbiome, and Reveals Unusual Bile Acids in Mice

Bile acids (BAs) are steroid detergents in bile that contribute to fat absorption, cell signaling, and microbiome interactions. The final step in their synthesis is amino acid conjugation with either glycine or taurine in the liver by the enzyme bile acid-CoA:amino acid N-acyltransferase (BAAT). Her...

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Detalles Bibliográficos
Autores principales: Neugebauer, Kerri A., Okros, Maxwell, Guzior, Douglas V., Feiner, Jeremiah, Chargo, Nicholas J., Rzepka, Madison, Schilmiller, Anthony L., O’Reilly, Sandra, Jones, A. Daniel, Watson, Victoria E., Luyendyk, James P., McCabe, Laura R., Quinn, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679037/
https://www.ncbi.nlm.nih.gov/pubmed/36243101
http://dx.doi.org/10.1016/j.jlr.2022.100297

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