A study of the DIBAL-promoted selective debenzylation of α-cyclodextrin protected with two different benzyl groups

An α-cyclodextrin protected with 2,4-dichlorobenzyl groups on the primary alcohols and ordinary benzyl groups on the secondary alcohols was prepared and subjected to DIBAL (diisobutylaluminum hydride)-promoted selective debenzylation. Debenzylation proceeded by first removing two dichlorobenzyl grou...

Descripción completa

Detalles Bibliográficos
Autores principales: Yousefi, Naser-Abdul, Zimmermann, Morten L, Bols, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679596/
https://www.ncbi.nlm.nih.gov/pubmed/36474968
http://dx.doi.org/10.3762/bjoc.18.165
_version_ 1784834229030354944
author Yousefi, Naser-Abdul
Zimmermann, Morten L
Bols, Mikael
author_facet Yousefi, Naser-Abdul
Zimmermann, Morten L
Bols, Mikael
author_sort Yousefi, Naser-Abdul
collection PubMed
description An α-cyclodextrin protected with 2,4-dichlorobenzyl groups on the primary alcohols and ordinary benzyl groups on the secondary alcohols was prepared and subjected to DIBAL (diisobutylaluminum hydride)-promoted selective debenzylation. Debenzylation proceeded by first removing two dichlorobenzyl groups from the 6(A,D) positions and then removing one or two benzyl groups from the 3(A,D) positions.
format Online
Article
Text
id pubmed-9679596
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-96795962022-12-05 A study of the DIBAL-promoted selective debenzylation of α-cyclodextrin protected with two different benzyl groups Yousefi, Naser-Abdul Zimmermann, Morten L Bols, Mikael Beilstein J Org Chem Full Research Paper An α-cyclodextrin protected with 2,4-dichlorobenzyl groups on the primary alcohols and ordinary benzyl groups on the secondary alcohols was prepared and subjected to DIBAL (diisobutylaluminum hydride)-promoted selective debenzylation. Debenzylation proceeded by first removing two dichlorobenzyl groups from the 6(A,D) positions and then removing one or two benzyl groups from the 3(A,D) positions. Beilstein-Institut 2022-11-17 /pmc/articles/PMC9679596/ /pubmed/36474968 http://dx.doi.org/10.3762/bjoc.18.165 Text en Copyright © 2022, Yousefi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjoc/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.
spellingShingle Full Research Paper
Yousefi, Naser-Abdul
Zimmermann, Morten L
Bols, Mikael
A study of the DIBAL-promoted selective debenzylation of α-cyclodextrin protected with two different benzyl groups
title A study of the DIBAL-promoted selective debenzylation of α-cyclodextrin protected with two different benzyl groups
title_full A study of the DIBAL-promoted selective debenzylation of α-cyclodextrin protected with two different benzyl groups
title_fullStr A study of the DIBAL-promoted selective debenzylation of α-cyclodextrin protected with two different benzyl groups
title_full_unstemmed A study of the DIBAL-promoted selective debenzylation of α-cyclodextrin protected with two different benzyl groups
title_short A study of the DIBAL-promoted selective debenzylation of α-cyclodextrin protected with two different benzyl groups
title_sort study of the dibal-promoted selective debenzylation of α-cyclodextrin protected with two different benzyl groups
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679596/
https://www.ncbi.nlm.nih.gov/pubmed/36474968
http://dx.doi.org/10.3762/bjoc.18.165
work_keys_str_mv AT yousefinaserabdul astudyofthedibalpromotedselectivedebenzylationofacyclodextrinprotectedwithtwodifferentbenzylgroups
AT zimmermannmortenl astudyofthedibalpromotedselectivedebenzylationofacyclodextrinprotectedwithtwodifferentbenzylgroups
AT bolsmikael astudyofthedibalpromotedselectivedebenzylationofacyclodextrinprotectedwithtwodifferentbenzylgroups
AT yousefinaserabdul studyofthedibalpromotedselectivedebenzylationofacyclodextrinprotectedwithtwodifferentbenzylgroups
AT zimmermannmortenl studyofthedibalpromotedselectivedebenzylationofacyclodextrinprotectedwithtwodifferentbenzylgroups
AT bolsmikael studyofthedibalpromotedselectivedebenzylationofacyclodextrinprotectedwithtwodifferentbenzylgroups

Ejemplares similares