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COVID-19 vaccination in patients with cancer: Opportunities and challenges

The rapid spread of the SARS-Cov-2 virus, the increase in the number of patients with severe COVID-19, and the high mortality rate created the basis for the production of safe and effective vaccines. Studies have confirmed the increased risk of severe Covid-19 disease and mortality in cancer patient...

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Autores principales: Al-qaim, Zahraa Haleem, Owadh, Hasanain Kamil Hasan, Ali, Sarah A., Hussein, Alaa S., Ameen, Thamer Ramadhan, Kolemen, Ayshan, Washi, Ghassan A., Jalil, Abduladheem Turki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679654/
https://www.ncbi.nlm.nih.gov/pubmed/36425557
http://dx.doi.org/10.3389/fonc.2022.1029325
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author Al-qaim, Zahraa Haleem
Owadh, Hasanain Kamil Hasan
Ali, Sarah A.
Hussein, Alaa S.
Ameen, Thamer Ramadhan
Kolemen, Ayshan
Washi, Ghassan A.
Jalil, Abduladheem Turki
author_facet Al-qaim, Zahraa Haleem
Owadh, Hasanain Kamil Hasan
Ali, Sarah A.
Hussein, Alaa S.
Ameen, Thamer Ramadhan
Kolemen, Ayshan
Washi, Ghassan A.
Jalil, Abduladheem Turki
author_sort Al-qaim, Zahraa Haleem
collection PubMed
description The rapid spread of the SARS-Cov-2 virus, the increase in the number of patients with severe COVID-19, and the high mortality rate created the basis for the production of safe and effective vaccines. Studies have confirmed the increased risk of severe Covid-19 disease and mortality in cancer patients. It is logical that cancer patients should be the first to receive the primary vaccination and the booster vaccine for Covid-19. Since studies related to cancer patients and the effectiveness of existing Covid-19 vaccines have not been widely conducted, there are significant uncertainties about the effectiveness of the vaccine and the level of humoral and cellular immune responses in these patients. As a result, the possible risks and side effects of existing vaccines are not clear for patients with different cancers who are undergoing special treatments. In this study, we will discuss the effectiveness and safety of existing vaccines on cancer patients. In addition, we highlight factors that could affect the effectiveness of vaccines in these patients and finally discuss opportunities and challenges related to vaccination in cancer patients.
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spelling pubmed-96796542022-11-23 COVID-19 vaccination in patients with cancer: Opportunities and challenges Al-qaim, Zahraa Haleem Owadh, Hasanain Kamil Hasan Ali, Sarah A. Hussein, Alaa S. Ameen, Thamer Ramadhan Kolemen, Ayshan Washi, Ghassan A. Jalil, Abduladheem Turki Front Oncol Oncology The rapid spread of the SARS-Cov-2 virus, the increase in the number of patients with severe COVID-19, and the high mortality rate created the basis for the production of safe and effective vaccines. Studies have confirmed the increased risk of severe Covid-19 disease and mortality in cancer patients. It is logical that cancer patients should be the first to receive the primary vaccination and the booster vaccine for Covid-19. Since studies related to cancer patients and the effectiveness of existing Covid-19 vaccines have not been widely conducted, there are significant uncertainties about the effectiveness of the vaccine and the level of humoral and cellular immune responses in these patients. As a result, the possible risks and side effects of existing vaccines are not clear for patients with different cancers who are undergoing special treatments. In this study, we will discuss the effectiveness and safety of existing vaccines on cancer patients. In addition, we highlight factors that could affect the effectiveness of vaccines in these patients and finally discuss opportunities and challenges related to vaccination in cancer patients. Frontiers Media S.A. 2022-11-08 /pmc/articles/PMC9679654/ /pubmed/36425557 http://dx.doi.org/10.3389/fonc.2022.1029325 Text en Copyright © 2022 Al-qaim, Owadh, Ali, Hussein, Ameen, Kolemen, Washi and Jalil https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Al-qaim, Zahraa Haleem
Owadh, Hasanain Kamil Hasan
Ali, Sarah A.
Hussein, Alaa S.
Ameen, Thamer Ramadhan
Kolemen, Ayshan
Washi, Ghassan A.
Jalil, Abduladheem Turki
COVID-19 vaccination in patients with cancer: Opportunities and challenges
title COVID-19 vaccination in patients with cancer: Opportunities and challenges
title_full COVID-19 vaccination in patients with cancer: Opportunities and challenges
title_fullStr COVID-19 vaccination in patients with cancer: Opportunities and challenges
title_full_unstemmed COVID-19 vaccination in patients with cancer: Opportunities and challenges
title_short COVID-19 vaccination in patients with cancer: Opportunities and challenges
title_sort covid-19 vaccination in patients with cancer: opportunities and challenges
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679654/
https://www.ncbi.nlm.nih.gov/pubmed/36425557
http://dx.doi.org/10.3389/fonc.2022.1029325
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