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Lipolysis-stimulated lipoprotein receptor-targeted antibody-drug conjugate demonstrates potent antitumor activity against epithelial ovarian cancer

BACKGROUND: Epithelial ovarian cancer (EOC) is a lethal malignant tumor, for which new treatment options are urgently required. Lipolysis-stimulated lipoprotein receptor (LSR) is widely expressed in EOC, and it is associated with poor prognosis. In this study, we developed an antibody-drug conjugate...

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Detalles Bibliográficos
Autores principales:	Kanda, Mizuki, Serada, Satoshi, Hiramatsu, Kosuke, Funauchi, Masashi, Obata, Kengo, Nakagawa, Satoshi, Ohkawara, Tomoharu, Murata, Okinori, Fujimoto, Minoru, Chiwaki, Fumiko, Sasaki, Hiroki, Ueda, Yutaka, Kimura, Tadashi, Naka, Tetsuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2022
Materias:	Original Research/Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679668/ https://www.ncbi.nlm.nih.gov/pubmed/36413881 http://dx.doi.org/10.1016/j.neo.2022.100853

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