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Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures

Leptospirosis is a global zoonotic bacterial disease which is a threat for humans and most mammals. Bacterin vaccines for leptospirosis are available however they are severely limited in cross protection between serogroups. Leptospira typically colonize the kidneys of reservoir hosts where they are...

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Autores principales: Putz, Ellie J., Fernandes, Luis G.V., Bayles, Darrell O., Lippolis, John D., Nally, Jarlath E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679693/
https://www.ncbi.nlm.nih.gov/pubmed/36425979
http://dx.doi.org/10.1016/j.dib.2022.108713
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author Putz, Ellie J.
Fernandes, Luis G.V.
Bayles, Darrell O.
Lippolis, John D.
Nally, Jarlath E.
author_facet Putz, Ellie J.
Fernandes, Luis G.V.
Bayles, Darrell O.
Lippolis, John D.
Nally, Jarlath E.
author_sort Putz, Ellie J.
collection PubMed
description Leptospirosis is a global zoonotic bacterial disease which is a threat for humans and most mammals. Bacterin vaccines for leptospirosis are available however they are severely limited in cross protection between serogroups. Leptospira typically colonize the kidneys of reservoir hosts where they are subsequently shed in the urine and persist in the environment and can thus be indirectly or directly transmitted to incidental hosts. Leptospira borgpetersenii serovar Hardjo is the primary cause of leptospirosis in cattle which can result in abortion, unhealthy calves, and rebreed problems. This dataset comprises proteomic profiles of four strains of L. borgpetersenii serovar Hardjo propagated at the routinely utilized culture temperature of 29 °C, and a newly achieved culture temperature of 37 °C, which more closely emulates the temperature of an infected host. The strains analyzed include JB197 (established strain that causes Hardjo atypical acute disease in the hamster model of leptospirosis), HB203 (established strain, causes typical chronic disease in hamsters), as well as TC129 and TC273 (recently isolated strains from the central United States). Differential expression profiles were detected not only between strains but also within strains between culture temperatures. Mass spectrometry data are available via ProteomeXchange with identifier PXD032831.
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spelling pubmed-96796932022-11-23 Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures Putz, Ellie J. Fernandes, Luis G.V. Bayles, Darrell O. Lippolis, John D. Nally, Jarlath E. Data Brief Data Article Leptospirosis is a global zoonotic bacterial disease which is a threat for humans and most mammals. Bacterin vaccines for leptospirosis are available however they are severely limited in cross protection between serogroups. Leptospira typically colonize the kidneys of reservoir hosts where they are subsequently shed in the urine and persist in the environment and can thus be indirectly or directly transmitted to incidental hosts. Leptospira borgpetersenii serovar Hardjo is the primary cause of leptospirosis in cattle which can result in abortion, unhealthy calves, and rebreed problems. This dataset comprises proteomic profiles of four strains of L. borgpetersenii serovar Hardjo propagated at the routinely utilized culture temperature of 29 °C, and a newly achieved culture temperature of 37 °C, which more closely emulates the temperature of an infected host. The strains analyzed include JB197 (established strain that causes Hardjo atypical acute disease in the hamster model of leptospirosis), HB203 (established strain, causes typical chronic disease in hamsters), as well as TC129 and TC273 (recently isolated strains from the central United States). Differential expression profiles were detected not only between strains but also within strains between culture temperatures. Mass spectrometry data are available via ProteomeXchange with identifier PXD032831. Elsevier 2022-10-29 /pmc/articles/PMC9679693/ /pubmed/36425979 http://dx.doi.org/10.1016/j.dib.2022.108713 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Putz, Ellie J.
Fernandes, Luis G.V.
Bayles, Darrell O.
Lippolis, John D.
Nally, Jarlath E.
Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures
title Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures
title_full Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures
title_fullStr Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures
title_full_unstemmed Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures
title_short Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures
title_sort proteomic dataset comparing strains of leptospira borgpetersenii serovar hardjo cultured at different temperatures
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679693/
https://www.ncbi.nlm.nih.gov/pubmed/36425979
http://dx.doi.org/10.1016/j.dib.2022.108713
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