Infections Simulating Immune Checkpoint Inhibitor Toxicities: Uncommon and Deceptive

Use of immune checkpoint inhibitors (ICIs), a revolutionary treatment in modern oncology, is frequently complicated by immune-related adverse events (irAEs), which can be confused with infections, and vice versa, thus complicating management decisions. In this study, we review the published cases of...

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Autores principales: Gudiol, Carlota, Hicklen, Rachel S, Okhyusen, Pablo C, Malek, Alexandre E, Kontoyiannis, Dimitrios P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679804/
https://www.ncbi.nlm.nih.gov/pubmed/36420059
http://dx.doi.org/10.1093/ofid/ofac570
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author Gudiol, Carlota
Hicklen, Rachel S
Okhyusen, Pablo C
Malek, Alexandre E
Kontoyiannis, Dimitrios P
author_facet Gudiol, Carlota
Hicklen, Rachel S
Okhyusen, Pablo C
Malek, Alexandre E
Kontoyiannis, Dimitrios P
author_sort Gudiol, Carlota
collection PubMed
description Use of immune checkpoint inhibitors (ICIs), a revolutionary treatment in modern oncology, is frequently complicated by immune-related adverse events (irAEs), which can be confused with infections, and vice versa, thus complicating management decisions. In this study, we review the published cases of infections as simulators of irAEs in cancer patients.
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spelling pubmed-96798042022-11-22 Infections Simulating Immune Checkpoint Inhibitor Toxicities: Uncommon and Deceptive Gudiol, Carlota Hicklen, Rachel S Okhyusen, Pablo C Malek, Alexandre E Kontoyiannis, Dimitrios P Open Forum Infect Dis Brief Report Use of immune checkpoint inhibitors (ICIs), a revolutionary treatment in modern oncology, is frequently complicated by immune-related adverse events (irAEs), which can be confused with infections, and vice versa, thus complicating management decisions. In this study, we review the published cases of infections as simulators of irAEs in cancer patients. Oxford University Press 2022-10-27 /pmc/articles/PMC9679804/ /pubmed/36420059 http://dx.doi.org/10.1093/ofid/ofac570 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Gudiol, Carlota
Hicklen, Rachel S
Okhyusen, Pablo C
Malek, Alexandre E
Kontoyiannis, Dimitrios P
Infections Simulating Immune Checkpoint Inhibitor Toxicities: Uncommon and Deceptive
title Infections Simulating Immune Checkpoint Inhibitor Toxicities: Uncommon and Deceptive
title_full Infections Simulating Immune Checkpoint Inhibitor Toxicities: Uncommon and Deceptive
title_fullStr Infections Simulating Immune Checkpoint Inhibitor Toxicities: Uncommon and Deceptive
title_full_unstemmed Infections Simulating Immune Checkpoint Inhibitor Toxicities: Uncommon and Deceptive
title_short Infections Simulating Immune Checkpoint Inhibitor Toxicities: Uncommon and Deceptive
title_sort infections simulating immune checkpoint inhibitor toxicities: uncommon and deceptive
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679804/
https://www.ncbi.nlm.nih.gov/pubmed/36420059
http://dx.doi.org/10.1093/ofid/ofac570
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