Specific Patterns of Immune Cell Dynamics May Explain the Early Onset and Prolonged Efficacy of Cladribine Tablets: A MAGNIFY-MS Substudy

BACKGROUND AND OBJECTIVES: Cladribine tablets cause a reduction in lymphocytes with a predominant effect on B-cell and T-cell counts. The MAGNIFY-MS substudy reports the dynamic changes on multiple peripheral blood mononuclear cell (PBMC) subtypes and immunoglobulin (Ig) levels over 12 months after...

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Detalles Bibliográficos
Autores principales: Wiendl, Heinz, Schmierer, Klaus, Hodgkinson, Suzanne, Derfuss, Tobias, Chan, Andrew, Sellebjerg, Finn, Achiron, Anat, Montalban, Xavier, Prat, Alexandre, De Stefano, Nicola, Barkhof, Frederik, Leocani, Letizia, Vermersch, Patrick, Chudecka, Anita, Mwape, Claire, Holmberg, Kristina H., Boschert, Ursula, Roy, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679889/
https://www.ncbi.nlm.nih.gov/pubmed/36411081
http://dx.doi.org/10.1212/NXI.0000000000200048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679889/
https://www.ncbi.nlm.nih.gov/pubmed/36411081
http://dx.doi.org/10.1212/NXI.0000000000200048

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