Altering the mRNA-1273 dosing interval impacts the kinetics, quality, and magnitude of immune responses in mice

For a vaccine to achieve durable immunity and optimal efficacy, many require a multi-dose primary vaccination schedule that acts to first “prime” naive immune systems and then “boost” initial immune responses by repeated immunizations (ie, prime-boost regimens). In the context of the global coronavi...

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Detalles Bibliográficos
Autores principales: Garcia-Dominguez, Dario, Henry, Carole, Ma, LingZhi, Jani, Hardik, Amato, Nicholas J., Manning, Taylor, Freyn, Alec, Davis, Heather, Hsiao, Chiaowen Joyce, Li, Mengying, Koch, Hillary, Elbashir, Sayda, DiPiazza, Anthony, Carfi, Andrea, Edwards, Darin, Bahl, Kapil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9679967/
https://www.ncbi.nlm.nih.gov/pubmed/36426367
http://dx.doi.org/10.3389/fimmu.2022.948335

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