Base-Mediated Nitrophenyl Reductive Cyclization for the Synthesis of Hexahydro-2,6-methano-1-benzazocines

[Image: see text] A Diels–Alder reaction leading to 4-nitrophenylcyclohexanones followed by a newly developed base-mediated reductive cyclization of the resulting ketone tethered to the nitrobenzene moiety gives access to the hexahydro-2,6-methano-1-benzazocine ring system present in several biologi...

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Detalles Bibliográficos
Autores principales: Rodríguez, Laura G., Delgado, Ana, Ciudad, Carlos J., Noé, Véronique, Bonjoch, Josep, Bradshaw, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680033/
https://www.ncbi.nlm.nih.gov/pubmed/36329560
http://dx.doi.org/10.1021/acs.joc.2c02205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680033/
https://www.ncbi.nlm.nih.gov/pubmed/36329560
http://dx.doi.org/10.1021/acs.joc.2c02205

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