Cyclin D1 mediates pain behaviour in a rat model of breast cancer-induced bone pain by a mechanism involving regulation of the proliferation of spinal microglia

AIMS: The involvement of cyclin D1 in the proliferation of microglia, and the generation and maintenance of bone cancer pain (BCP), have not yet been clarified. We investigated the expression of microglia and cyclin D1, and the influences of cyclin D1 on pain threshold. METHODS: Female Sprague Dawle...

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Detalles Bibliográficos
Autores principales: Guan, Xuehai, Gong, Xiaofang, Jiao, Ziyin Y., Cao, Huiyu Y., Liu, Susu, Lin, Chengxin, Huang, Xiaofang, Lan, Hongmeng, Ma, Li, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2022
Materias:
Bone Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680203/
https://www.ncbi.nlm.nih.gov/pubmed/36374014
http://dx.doi.org/10.1302/2046-3758.1111.BJR-2022-0018.R1

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