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Doxycycline Induced Pancreatitis: An Uncommon Complication of a Common Drug

We describe the risk factors for the development, timing, and severity of doxycycline induced acute pancreatitis (DIAP) in two case reports and a review of prior published cases, to better understand DIAP. Clinicians must maintain a high level of suspicion for DIAP in patients presenting with acute...

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Detalles Bibliográficos
Autores principales: Reiche, William, Abodunrin, Faith, Destache, Chris, Rangray, Rajani, Velagapudi, Manasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680210/
https://www.ncbi.nlm.nih.gov/pubmed/36412820
http://dx.doi.org/10.3390/pharmacy10060144
Descripción
Sumario:We describe the risk factors for the development, timing, and severity of doxycycline induced acute pancreatitis (DIAP) in two case reports and a review of prior published cases, to better understand DIAP. Clinicians must maintain a high level of suspicion for DIAP in patients presenting with acute pancreatitis, while on doxycycline therapy. The latency and severity of DIAP are variable, making diagnosis challenging. Treatment includes bowel rest, hydration, and discontinuation of doxycycline.