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Imaging or Adrenal Vein Sampling Approach in Primary Aldosteronism? A Patient-Based Approach

Primary aldosteronism (PA) is the most frequent cause of secondary hypertension, associated with an increased risk of cardiovascular and cerebral disease, compared to essential hypertension. Therefore, it is mandatory to promptly recognize the disease and offer to the patient the correct diagnostic–...

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Autores principales: Tizianel, Irene, Sabbadin, Chiara, Mian, Caterina, Scaroni, Carla, Ceccato, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680373/
https://www.ncbi.nlm.nih.gov/pubmed/36412687
http://dx.doi.org/10.3390/tomography8060228
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author Tizianel, Irene
Sabbadin, Chiara
Mian, Caterina
Scaroni, Carla
Ceccato, Filippo
author_facet Tizianel, Irene
Sabbadin, Chiara
Mian, Caterina
Scaroni, Carla
Ceccato, Filippo
author_sort Tizianel, Irene
collection PubMed
description Primary aldosteronism (PA) is the most frequent cause of secondary hypertension, associated with an increased risk of cardiovascular and cerebral disease, compared to essential hypertension. Therefore, it is mandatory to promptly recognize the disease and offer to the patient the correct diagnostic–therapeutic process in order to reduce new-onset cardiovascular events. It is fundamental to define subtype classification (unilateral or bilateral disease), in order to provide the best treatment (surgery for unilateral and medical treatment for bilateral disease). Here, we report five clinical cases of different subtypes of PA (patients with monolateral or bilateral PA, nondiagnostic AVS, allergy to iodinated contrast, and patients not suitable for surgery), with particular attention to the diagnostic–therapeutic process and the different approaches tailored to a single case. Since PA is a spectrum of various diseases, it needs a personalized diagnostic–therapeutic process, customized for the individual patient, depending on previous medical history, suitability for the surgery and patient’s preferences.
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spelling pubmed-96803732022-11-23 Imaging or Adrenal Vein Sampling Approach in Primary Aldosteronism? A Patient-Based Approach Tizianel, Irene Sabbadin, Chiara Mian, Caterina Scaroni, Carla Ceccato, Filippo Tomography Review Primary aldosteronism (PA) is the most frequent cause of secondary hypertension, associated with an increased risk of cardiovascular and cerebral disease, compared to essential hypertension. Therefore, it is mandatory to promptly recognize the disease and offer to the patient the correct diagnostic–therapeutic process in order to reduce new-onset cardiovascular events. It is fundamental to define subtype classification (unilateral or bilateral disease), in order to provide the best treatment (surgery for unilateral and medical treatment for bilateral disease). Here, we report five clinical cases of different subtypes of PA (patients with monolateral or bilateral PA, nondiagnostic AVS, allergy to iodinated contrast, and patients not suitable for surgery), with particular attention to the diagnostic–therapeutic process and the different approaches tailored to a single case. Since PA is a spectrum of various diseases, it needs a personalized diagnostic–therapeutic process, customized for the individual patient, depending on previous medical history, suitability for the surgery and patient’s preferences. MDPI 2022-11-09 /pmc/articles/PMC9680373/ /pubmed/36412687 http://dx.doi.org/10.3390/tomography8060228 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Tizianel, Irene
Sabbadin, Chiara
Mian, Caterina
Scaroni, Carla
Ceccato, Filippo
Imaging or Adrenal Vein Sampling Approach in Primary Aldosteronism? A Patient-Based Approach
title Imaging or Adrenal Vein Sampling Approach in Primary Aldosteronism? A Patient-Based Approach
title_full Imaging or Adrenal Vein Sampling Approach in Primary Aldosteronism? A Patient-Based Approach
title_fullStr Imaging or Adrenal Vein Sampling Approach in Primary Aldosteronism? A Patient-Based Approach
title_full_unstemmed Imaging or Adrenal Vein Sampling Approach in Primary Aldosteronism? A Patient-Based Approach
title_short Imaging or Adrenal Vein Sampling Approach in Primary Aldosteronism? A Patient-Based Approach
title_sort imaging or adrenal vein sampling approach in primary aldosteronism? a patient-based approach
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680373/
https://www.ncbi.nlm.nih.gov/pubmed/36412687
http://dx.doi.org/10.3390/tomography8060228
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