Cargando…

Review on Biocompatibility and Prospect Biomedical Applications of Novel Functional Metallic Glasses

The continuous development of novel materials for biomedical applications is resulting in an increasingly better prognosis for patients. The application of more advanced materials relates to fewer complications and a desirable higher percentage of successful treatments. New, innovative materials bei...

Descripción completa

Detalles Bibliográficos
Autores principales: Biały, Michał, Hasiak, Mariusz, Łaszcz, Amadeusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680474/
https://www.ncbi.nlm.nih.gov/pubmed/36412886
http://dx.doi.org/10.3390/jfb13040245
_version_ 1784834426789691392
author Biały, Michał
Hasiak, Mariusz
Łaszcz, Amadeusz
author_facet Biały, Michał
Hasiak, Mariusz
Łaszcz, Amadeusz
author_sort Biały, Michał
collection PubMed
description The continuous development of novel materials for biomedical applications is resulting in an increasingly better prognosis for patients. The application of more advanced materials relates to fewer complications and a desirable higher percentage of successful treatments. New, innovative materials being considered for biomedical applications are metallic alloys with an amorphous internal structure called metallic glasses. They are currently in a dynamic phase of development both in terms of formulating new chemical compositions and testing their properties in terms of intended biocompatibility. This review article intends to synthesize the latest research results in the field of biocompatible metallic glasses to create a more coherent picture of these materials. It summarizes and discusses the most recent findings in the areas of mechanical properties, corrosion resistance, in vitro cellular studies, antibacterial properties, and in vivo animal studies. Results are collected mainly for the most popular metallic glasses manufactured as thin films, coatings, and in bulk form. Considered materials include alloys based on zirconium and titanium, as well as new promising ones based on magnesium, tantalum, and palladium. From the properties of the examined metallic glasses, possible areas of application and further research directions to fill existing gaps are proposed.
format Online
Article
Text
id pubmed-9680474
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96804742022-11-23 Review on Biocompatibility and Prospect Biomedical Applications of Novel Functional Metallic Glasses Biały, Michał Hasiak, Mariusz Łaszcz, Amadeusz J Funct Biomater Review The continuous development of novel materials for biomedical applications is resulting in an increasingly better prognosis for patients. The application of more advanced materials relates to fewer complications and a desirable higher percentage of successful treatments. New, innovative materials being considered for biomedical applications are metallic alloys with an amorphous internal structure called metallic glasses. They are currently in a dynamic phase of development both in terms of formulating new chemical compositions and testing their properties in terms of intended biocompatibility. This review article intends to synthesize the latest research results in the field of biocompatible metallic glasses to create a more coherent picture of these materials. It summarizes and discusses the most recent findings in the areas of mechanical properties, corrosion resistance, in vitro cellular studies, antibacterial properties, and in vivo animal studies. Results are collected mainly for the most popular metallic glasses manufactured as thin films, coatings, and in bulk form. Considered materials include alloys based on zirconium and titanium, as well as new promising ones based on magnesium, tantalum, and palladium. From the properties of the examined metallic glasses, possible areas of application and further research directions to fill existing gaps are proposed. MDPI 2022-11-16 /pmc/articles/PMC9680474/ /pubmed/36412886 http://dx.doi.org/10.3390/jfb13040245 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Biały, Michał
Hasiak, Mariusz
Łaszcz, Amadeusz
Review on Biocompatibility and Prospect Biomedical Applications of Novel Functional Metallic Glasses
title Review on Biocompatibility and Prospect Biomedical Applications of Novel Functional Metallic Glasses
title_full Review on Biocompatibility and Prospect Biomedical Applications of Novel Functional Metallic Glasses
title_fullStr Review on Biocompatibility and Prospect Biomedical Applications of Novel Functional Metallic Glasses
title_full_unstemmed Review on Biocompatibility and Prospect Biomedical Applications of Novel Functional Metallic Glasses
title_short Review on Biocompatibility and Prospect Biomedical Applications of Novel Functional Metallic Glasses
title_sort review on biocompatibility and prospect biomedical applications of novel functional metallic glasses
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680474/
https://www.ncbi.nlm.nih.gov/pubmed/36412886
http://dx.doi.org/10.3390/jfb13040245
work_keys_str_mv AT białymichał reviewonbiocompatibilityandprospectbiomedicalapplicationsofnovelfunctionalmetallicglasses
AT hasiakmariusz reviewonbiocompatibilityandprospectbiomedicalapplicationsofnovelfunctionalmetallicglasses
AT łaszczamadeusz reviewonbiocompatibilityandprospectbiomedicalapplicationsofnovelfunctionalmetallicglasses