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Synthesis, Biophysical Interaction of DNA/BSA, Equilibrium and Stopped-Flow Kinetic Studies, and Biological Evaluation of bis(2-Picolyl)amine-Based Nickel(II) Complex

Reaction of bis(2-picolyl)amine (BPA) with Ni(II) salt yielded [(BPA)NiCl(2)(H(2)O)] (NiBPA). The Ni(II) in NiBPA bound to a BPA ligand, two chloride, and one aqua ligands. Because most medications inhibit biological processes by binding to a specific protein, the stopped-flow technique was used to...

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Detalles Bibliográficos
Autores principales:	Ramzy, Esraa, Ibrahim, Mohamed M., El-Mehasseb, Ibrahim M., Ramadan, Abd El-Motaleb M., Elshami, Fawzia I., Shaban, Shaban Y., van Eldik, Rudi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680484/ https://www.ncbi.nlm.nih.gov/pubmed/36412701 http://dx.doi.org/10.3390/biomimetics7040172

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