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Type 2 Diabetes Mellitus Makes Corneal Endothelial Cells Vulnerable to Ultraviolet A-Induced Oxidative Damage Via Decreased DJ-1/Nrf2/NQO1 Pathway

PURPOSE: The purpose of this study was to investigate whether type 2 diabetes mellitus (T2DM) makes corneal endothelial cells (CECs) suffer from more severe ultraviolet A (UVA)-induced oxidative damage and explore its mechanisms via measuring the oxidant level and the antioxidant level in vitro. MET...

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Detalles Bibliográficos
Autores principales: Zhang, Xueling, Qiu, Jini, Huang, Feifei, Shan, Kun, Zhang, Chaoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680587/
https://www.ncbi.nlm.nih.gov/pubmed/36383351
http://dx.doi.org/10.1167/iovs.63.12.25