Permissive and nonpermissive channel closings in CFTR revealed by a factor graph inference algorithm

The closing of the gated ion channel in the cystic fibrosis transmembrane conductance regulator can be categorized as nonpermissive to reopening, which involves the unbinding of ADP or ATP, or permissive, which does not. Identifying the type of closing is of interest as interactions with nucleotides...

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Detalles Bibliográficos
Autores principales: Moffett, Alexander S., Cui, Guiying, Thomas, Peter J., Hunt, William D., McCarty, Nael A., Westafer, Ryan S., Eckford, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680790/
https://www.ncbi.nlm.nih.gov/pubmed/36425670
http://dx.doi.org/10.1016/j.bpr.2022.100083

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