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Merits of Diazirine Photo-Immobilization for Target Profiling of Natural Products and Cofactors

[Image: see text] Finding the targets of natural products is of key importance in both chemical biology and drug discovery, and deconvolution of cofactor interactomes contributes to the functional annotation of the proteome. Identifying the proteins that underlie natural compound activity in phenoty...

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Detalles Bibliográficos
Autores principales: Prokofeva, Polina, Höfer, Stefanie, Hornisch, Maximilian, Abele, Miriam, Kuster, Bernhard, Médard, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680877/
https://www.ncbi.nlm.nih.gov/pubmed/36302507
http://dx.doi.org/10.1021/acschembio.2c00500