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Co-infections in Hospitalized COVID-19 Patients- A Prospective Observational Study
Introduction: SARS -CoV-2 was first reported in Wuhan and declared a pandemic in March 2020. Co-infections during other pandemics have been associated with severe outcomes, but data are scarce regarding co-infections in COVID-19 patients. Our study evaluated co-infections prevalence and its impact o...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680979/ https://www.ncbi.nlm.nih.gov/pubmed/36426311 http://dx.doi.org/10.7759/cureus.30608 |
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author | Jalandra, Ramniwas Babu, Avinash Dutt, Naveen Chauhan, Nishant Kumar Bhatia, Pradeep Nag, Vijaya L Sharma, Praveen Kumar, Deepak Banerjee, Mithu Joshi, Aditi |
author_facet | Jalandra, Ramniwas Babu, Avinash Dutt, Naveen Chauhan, Nishant Kumar Bhatia, Pradeep Nag, Vijaya L Sharma, Praveen Kumar, Deepak Banerjee, Mithu Joshi, Aditi |
author_sort | Jalandra, Ramniwas |
collection | PubMed |
description | Introduction: SARS -CoV-2 was first reported in Wuhan and declared a pandemic in March 2020. Co-infections during other pandemics have been associated with severe outcomes, but data are scarce regarding co-infections in COVID-19 patients. Our study evaluated co-infections prevalence and its impact on morbidity and mortality in hospitalized COVID -19 patients. Methods: This prospective observational study included 100 patients admitted to a high-dependency unit at a tertiary care hospital in India. Prevalence of co-infections and clinical outcome-related data were analyzed in COVID-19 patients satisfying the inclusion criteria. Results: 14% of patients had co-infections, out of which urinary tract infection was found in 9%. Patients with co-infections had a higher mortality rate (p<0.0004). Urinary co-infection emerged as an independent risk factor for mortality (p <0.001). Conclusion: Co-infections associated with COVID-19 infections are an essential risk factor for morbidity and mortality. Early identification and timely treatment of co-infections may help in improving clinical outcomes. |
format | Online Article Text |
id | pubmed-9680979 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-96809792022-11-23 Co-infections in Hospitalized COVID-19 Patients- A Prospective Observational Study Jalandra, Ramniwas Babu, Avinash Dutt, Naveen Chauhan, Nishant Kumar Bhatia, Pradeep Nag, Vijaya L Sharma, Praveen Kumar, Deepak Banerjee, Mithu Joshi, Aditi Cureus Internal Medicine Introduction: SARS -CoV-2 was first reported in Wuhan and declared a pandemic in March 2020. Co-infections during other pandemics have been associated with severe outcomes, but data are scarce regarding co-infections in COVID-19 patients. Our study evaluated co-infections prevalence and its impact on morbidity and mortality in hospitalized COVID -19 patients. Methods: This prospective observational study included 100 patients admitted to a high-dependency unit at a tertiary care hospital in India. Prevalence of co-infections and clinical outcome-related data were analyzed in COVID-19 patients satisfying the inclusion criteria. Results: 14% of patients had co-infections, out of which urinary tract infection was found in 9%. Patients with co-infections had a higher mortality rate (p<0.0004). Urinary co-infection emerged as an independent risk factor for mortality (p <0.001). Conclusion: Co-infections associated with COVID-19 infections are an essential risk factor for morbidity and mortality. Early identification and timely treatment of co-infections may help in improving clinical outcomes. Cureus 2022-10-23 /pmc/articles/PMC9680979/ /pubmed/36426311 http://dx.doi.org/10.7759/cureus.30608 Text en Copyright © 2022, Jalandra et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Jalandra, Ramniwas Babu, Avinash Dutt, Naveen Chauhan, Nishant Kumar Bhatia, Pradeep Nag, Vijaya L Sharma, Praveen Kumar, Deepak Banerjee, Mithu Joshi, Aditi Co-infections in Hospitalized COVID-19 Patients- A Prospective Observational Study |
title | Co-infections in Hospitalized COVID-19 Patients- A Prospective Observational Study |
title_full | Co-infections in Hospitalized COVID-19 Patients- A Prospective Observational Study |
title_fullStr | Co-infections in Hospitalized COVID-19 Patients- A Prospective Observational Study |
title_full_unstemmed | Co-infections in Hospitalized COVID-19 Patients- A Prospective Observational Study |
title_short | Co-infections in Hospitalized COVID-19 Patients- A Prospective Observational Study |
title_sort | co-infections in hospitalized covid-19 patients- a prospective observational study |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680979/ https://www.ncbi.nlm.nih.gov/pubmed/36426311 http://dx.doi.org/10.7759/cureus.30608 |
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