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Cognitive Impairment and Neuropsychiatry Manifestation Following Mild and Moderate Traumatic Brain Injury at 3 Months and 6 Months

BACKGROUND: Cognitive impairment (CI) and neuropsychiatry manifestation (NM) are known complications among patients with traumatic brain injury (TBI). However, the clinical correlation between mild and moderate TBI with the above have not been extensively studied. METHODS: The patients (n = 54) were...

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Autores principales: Othman, Aizzat, Idris, Zamzuri, Rosman, Azmin Kass, Abdullah, Jafri Malin, GhanI, Abdul Rahman Izaini, Zakaria, Ahmad Zabidin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Penerbit Universiti Sains Malaysia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680998/
https://www.ncbi.nlm.nih.gov/pubmed/36474530
http://dx.doi.org/10.21315/mjms2022.29.5.6
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author Othman, Aizzat
Idris, Zamzuri
Rosman, Azmin Kass
Abdullah, Jafri Malin
GhanI, Abdul Rahman Izaini
Zakaria, Ahmad Zabidin
author_facet Othman, Aizzat
Idris, Zamzuri
Rosman, Azmin Kass
Abdullah, Jafri Malin
GhanI, Abdul Rahman Izaini
Zakaria, Ahmad Zabidin
author_sort Othman, Aizzat
collection PubMed
description BACKGROUND: Cognitive impairment (CI) and neuropsychiatry manifestation (NM) are known complications among patients with traumatic brain injury (TBI). However, the clinical correlation between mild and moderate TBI with the above have not been extensively studied. METHODS: The patients (n = 54) were divided into mild and moderate TBI. Both groups were assessed at 3 months and 6 months post-trauma for the same measures. Diagnosis of CI was done using the Montreal cognitive assessment (MoCA) questionnaire while NM screening was performed using the 12-items General Health Questionnaire (GHQ-12) followed by MINI International Neuropsychiatry Interview (MINI). RESULTS: We found five patients (19.2%) with mild TBI had CI and five patients (19.2%) had NM at 3 months. Only one patient (3.8%) persistently has CI at 6 months while the rest recovered. As for moderate TBI, 11 patients (39.3%) had CI and seven patients (25%) had NM at 3 months but none had persistent CI or NM at 6 months. Age (P < 0.05) and blood pressure were significant risks (P < 0.05) for CI and NM at 3 months. CONCLUSION: This study highlighted the importance of screening following mild and moderate TBI at 3 months and 6 months. Early recognition facilitates effective rehabilitation programmes planning hence improve prognosis in the future.
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spelling pubmed-96809982022-12-05 Cognitive Impairment and Neuropsychiatry Manifestation Following Mild and Moderate Traumatic Brain Injury at 3 Months and 6 Months Othman, Aizzat Idris, Zamzuri Rosman, Azmin Kass Abdullah, Jafri Malin GhanI, Abdul Rahman Izaini Zakaria, Ahmad Zabidin Malays J Med Sci Original Article BACKGROUND: Cognitive impairment (CI) and neuropsychiatry manifestation (NM) are known complications among patients with traumatic brain injury (TBI). However, the clinical correlation between mild and moderate TBI with the above have not been extensively studied. METHODS: The patients (n = 54) were divided into mild and moderate TBI. Both groups were assessed at 3 months and 6 months post-trauma for the same measures. Diagnosis of CI was done using the Montreal cognitive assessment (MoCA) questionnaire while NM screening was performed using the 12-items General Health Questionnaire (GHQ-12) followed by MINI International Neuropsychiatry Interview (MINI). RESULTS: We found five patients (19.2%) with mild TBI had CI and five patients (19.2%) had NM at 3 months. Only one patient (3.8%) persistently has CI at 6 months while the rest recovered. As for moderate TBI, 11 patients (39.3%) had CI and seven patients (25%) had NM at 3 months but none had persistent CI or NM at 6 months. Age (P < 0.05) and blood pressure were significant risks (P < 0.05) for CI and NM at 3 months. CONCLUSION: This study highlighted the importance of screening following mild and moderate TBI at 3 months and 6 months. Early recognition facilitates effective rehabilitation programmes planning hence improve prognosis in the future. Penerbit Universiti Sains Malaysia 2022-10 2022-10-28 /pmc/articles/PMC9680998/ /pubmed/36474530 http://dx.doi.org/10.21315/mjms2022.29.5.6 Text en © Penerbit Universiti Sains Malaysia, 2022 https://creativecommons.org/licenses/by/4.0/This work is licensed under the terms of the Creative Commons Attribution (CC BY) (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Original Article
Othman, Aizzat
Idris, Zamzuri
Rosman, Azmin Kass
Abdullah, Jafri Malin
GhanI, Abdul Rahman Izaini
Zakaria, Ahmad Zabidin
Cognitive Impairment and Neuropsychiatry Manifestation Following Mild and Moderate Traumatic Brain Injury at 3 Months and 6 Months
title Cognitive Impairment and Neuropsychiatry Manifestation Following Mild and Moderate Traumatic Brain Injury at 3 Months and 6 Months
title_full Cognitive Impairment and Neuropsychiatry Manifestation Following Mild and Moderate Traumatic Brain Injury at 3 Months and 6 Months
title_fullStr Cognitive Impairment and Neuropsychiatry Manifestation Following Mild and Moderate Traumatic Brain Injury at 3 Months and 6 Months
title_full_unstemmed Cognitive Impairment and Neuropsychiatry Manifestation Following Mild and Moderate Traumatic Brain Injury at 3 Months and 6 Months
title_short Cognitive Impairment and Neuropsychiatry Manifestation Following Mild and Moderate Traumatic Brain Injury at 3 Months and 6 Months
title_sort cognitive impairment and neuropsychiatry manifestation following mild and moderate traumatic brain injury at 3 months and 6 months
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9680998/
https://www.ncbi.nlm.nih.gov/pubmed/36474530
http://dx.doi.org/10.21315/mjms2022.29.5.6
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