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The serum acylcarnitines profile in epileptic children treated with valproic acid and the protective roles of peroxisome proliferator-activated receptor a activation in valproic acid-induced liver injury

Valproic acid (VPA) is widely used as a major drug in the treatment of epilepsy. Despite the undisputed pharmacological importance and effectiveness of VPA, its potential hepatotoxicity is still a major concern. Being a simple fatty acid, the hepatotoxicity induced by VPA has long been considered to...

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Detalles Bibliográficos
Autores principales: Ma, Yiyi, Wang, Minglu, Guo, Shuaishuai, Li, Tong, Liu, Xiaodong, Zhao, Limei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681037/
https://www.ncbi.nlm.nih.gov/pubmed/36425583
http://dx.doi.org/10.3389/fphar.2022.1048728