A C57BL/6 Mouse model of SARS-CoV-2 infection recapitulates age- and sex-based differences in human COVID-19 disease and recovery

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We present a comprehensive analysis of SARS-CoV-2 infection and recovery in wild type C57BL/6 mice, demonstrating that this is an ideal model of infection and recovery that accurately phenocopies acute human disease arising from the ancestral SARS-CoV-2. Disease severity and infection kinetics are a...

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Detalles Bibliográficos
Autores principales: Davis, Michael, Voss, Kathleen, Turnbull, J. Bryan, Gustin, Andrew T., Knoll, Megan, Muruato, Antonio, Hsiang, Tien-Ying, Dinnon, Kenneth H., Leist, Sarah R., Nickel, Katie, Baric, Ralph S., Ladiges, Warren, Akilesh, Shreeram, Smith, Kelly D., Gale, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681052/
https://www.ncbi.nlm.nih.gov/pubmed/36415465
http://dx.doi.org/10.21203/rs.3.rs-2194450/v1
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