Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients

Intra-tumor heterogeneity (ITH) of human tumors is important for tumor progression, treatment response, and drug resistance. However, the spatial distribution of ITH remains incompletely understood. Here, we present spatial analysis of ITH in lung adenocarcinomas from 147 patients using multi-region...

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Detalles Bibliográficos
Autores principales: Wu, Hua-Jun, Temko, Daniel, Maliga, Zoltan, Moreira, Andre L., Sei, Emi, Minussi, Darlan Conterno, Dean, Jamie, Lee, Charlotte, Xu, Qiong, Hochart, Guillaume, Jacobson, Connor A., Yapp, Clarence, Schapiro, Denis, Sorger, Peter K., Seeley, Erin H., Navin, Nicholas, Downey, Robert J., Michor, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681138/
https://www.ncbi.nlm.nih.gov/pubmed/36419822
http://dx.doi.org/10.1016/j.xgen.2022.100165

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