Biological network topology features predict gene dependencies in cancer cell-lines

MOTIVATION: Protein–protein interaction (PPI) networks have been shown to successfully predict essential proteins. However, such networks are derived generically from experiments on many thousands of different cells. Consequently, conventional PPI networks cannot capture the variation of genetic dep...

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Detalles Bibliográficos
Autores principales: Benstead-Hume, Graeme, Wooller, Sarah K, Renaut, Joanna, Dias, Samantha, Woodbine, Lisa, Carr, Antony M, Pearl, Frances M G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681200/
https://www.ncbi.nlm.nih.gov/pubmed/36699394
http://dx.doi.org/10.1093/bioadv/vbac084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681200/
https://www.ncbi.nlm.nih.gov/pubmed/36699394
http://dx.doi.org/10.1093/bioadv/vbac084

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