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Biological network topology features predict gene dependencies in cancer cell-lines
MOTIVATION: Protein–protein interaction (PPI) networks have been shown to successfully predict essential proteins. However, such networks are derived generically from experiments on many thousands of different cells. Consequently, conventional PPI networks cannot capture the variation of genetic dep...
Autores principales: | Benstead-Hume, Graeme, Wooller, Sarah K, Renaut, Joanna, Dias, Samantha, Woodbine, Lisa, Carr, Antony M, Pearl, Frances M G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681200/ https://www.ncbi.nlm.nih.gov/pubmed/36699394 http://dx.doi.org/10.1093/bioadv/vbac084 |
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