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San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway

San-Huang-Yi-Shen capsule (SHYS) has been used in the treatment of diabetic kidney disease (DKD) in clinics. However, the mechanism of SHYS on DKD remains unclear. In this study, we used a high-fat diet combined with streptozocin (STZ) injection to establish a rat model of DKD, and different doses o...

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Detalles Bibliográficos
Autores principales: Li, Hanzhou, Wang, Yuansong, Su, Xiuhai, Wang, Qinghai, Zhang, Shufang, Sun, Wenjuan, Zhang, Tianyu, Dong, Mengxue, Zhang, Zhaiyi, Lv, Shuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681560/
https://www.ncbi.nlm.nih.gov/pubmed/36425593
http://dx.doi.org/10.1155/2022/2640209