Cargando…

Pilot Study: PARP1 Imaging in Advanced Prostate Cancer

PURPOSE: PARP inhibitor (PARPi) therapy is approved for patients with metastatic castration-resistant prostate cancer (mCRPC) and homologous recombination repair (HRR) genomic aberrations. However, only a fraction of patients with BRCA1/2 mutations respond to PARPi therapy. In this pilot study, we a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dehdashti, Farrokh, Reimers, Melissa A., Shoghi, Kooresh I., Chen, Delphine L., Luo, Jingqin, Rogers, Buck, Pachynski, Russell K., Sreekumar, Sreeja, Weimholt, Cody, Zhou, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Brief Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681698/ https://www.ncbi.nlm.nih.gov/pubmed/35701722 http://dx.doi.org/10.1007/s11307-022-01746-w

Ejemplares similares

Preclinical Efficacy of a PARP-1 Targeted Auger-Emitting Radionuclide in Prostate Cancer
por: Sreekumar, Sreeja, et al.
Publicado: (2023)

Correction to: Co‑clinical FDG‑PET radiomic signature in predicting response to neoadjuvant chemotherapy in triple‑negative breast cancer
por: Roy, Sudipta, et al.
Publicado: (2021)

Co-clinical FDG-PET radiomic signature in predicting response to neoadjuvant chemotherapy in triple-negative breast cancer
por: Roy, Sudipta, et al.
Publicado: (2021)

Immunotherapy and Immunotherapy Combinations in Metastatic Castration-Resistant Prostate Cancer
por: Bansal, Dhruv, et al.
Publicado: (2021)

Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance
por: Sridaran, Dhivya, et al.
Publicado: (2022)

Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer
por: Nguyen, Thanh, et al.
Publicado: (2023)

Author Correction: Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer
por: Nguyen, Thanh, et al.
Publicado: (2023)

First-in-Humans Evaluation of Safety and Dosimetry of (64)Cu-LLP2A for PET Imaging
por: Laforest, Richard, et al.
Publicado: (2023)

In Vivo Multi-Tissue Efficacy of Peroxisome Proliferator-Activated Receptor-γ Therapy on Glucose and Fatty Acid Metabolism in Obese Type 2 Diabetic Rats
por: Nemanich, Samuel, et al.
Publicado: (2013)

A comparison of (64)Cu-labeled bi-terminally PEGylated A20FMDV2 peptides targeting integrin α(ν)β(6)
por: Huynh, Truc T., et al.
Publicado: (2022)

Videos of Sipuleucel-T Programmed T Cells Lysing Cells That Express Prostate Cancer Target Antigens
por: Kibel, Adam S, et al.
Publicado: (2021)

Therapeutic Efficacy of (177)Lu-Labeled A20FMDV2 Peptides Targeting α(ν)β(6)
por: Huynh, Truc Thao, et al.
Publicado: (2022)

Deep Learning Segmentation of Triple-Negative Breast Cancer (TNBC) Patient Derived Tumor Xenograft (PDX) and Sensitivity of Radiomic Pipeline to Tumor Probability Boundary
por: Dutta, Kaushik, et al.
Publicado: (2021)

Advances in PARP Inhibitors for Prostate Cancer
por: Tisseverasinghe, Steven, et al.
Publicado: (2023)

Copper-67-Labeled Bombesin Peptide for Targeted Radionuclide Therapy of Prostate Cancer
por: Huynh, Truc T., et al.
Publicado: (2022)

[(18)F]-Labeled PARP-1 PET imaging of PSMA targeted alpha particle radiotherapy response
por: Zhang, Hanwen, et al.
Publicado: (2022)

TNK2/ACK1-mediated phosphorylation of ATP5F1A (ATP synthase F1 subunit alpha) selectively augments survival of prostate cancer while engendering mitochondrial vulnerability
por: Chouhan, Surbhi, et al.
Publicado: (2022)

Pan-cancer distribution of cleaved cell-surface amphiregulin, the target of the GMF-1A3 antibody drug conjugate
por: Lofgren, Kristopher A, et al.
Publicado: (2022)

47149 Imaging Tools for Early Detection of Kidney Disease.
por: Baldelomar, Edwin J., et al.
Publicado: (2021)

Whole slide image with image analysis of atypical bile duct brushing: Quantitative features predictive of malignancy
por: Collins, Brian T., et al.
Publicado: (2015)

PARP Inhibitors as Monotherapy in Daily Practice for Advanced Prostate Cancers
por: Teyssonneau, Diego, et al.
Publicado: (2022)

PARP-1 protein expression in glioblastoma multiforme
por: Galia, A., et al.
Publicado: (2012)

Genomic and Metabolic Disposition of Non-Obese Type 2 Diabetic Rats to Increased Myocardial Fatty Acid Metabolism
por: Devanathan, Sriram, et al.
Publicado: (2013)

PARP Inhibitors in Advanced Prostate Cancer in Tumors with DNA Damage Signatures
por: McNevin, Ciara S., et al.
Publicado: (2022)

Molecular imaging of bone metastasis
por: Khojasteh, Eliana, et al.
Publicado: (2023)

Sexual dimorphism in myocardial acylcarnitine and triglyceride metabolism
por: Devanathan, Sriram, et al.
Publicado: (2016)

The Role of PARP Inhibitors in the Treatment of Prostate Cancer: Recent Advances in Clinical Trials
por: Xia, Mingyue, et al.
Publicado: (2021)

Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting
por: Sawant, Mithila, et al.
Publicado: (2022)

Frequency of Hepatic Metastatic Disease in Patients with Stage IV Breast Cancer Is Similar for Steatotic and Non-Steatotic Livers
por: Haq, Adeel, et al.
Publicado: (2023)

PARP inhibitor combinations in prostate cancer
por: Pezaro, Carmel
Publicado: (2020)

PARP Inhibitors in Prostate and Urothelial Cancers
por: Garje, Rohan, et al.
Publicado: (2020)

PARP inhibitors in metastatic prostate cancer
por: Taylor, Amy K., et al.
Publicado: (2023)

Advances and perspectives of PARP inhibitors
por: Yi, Ming, et al.
Publicado: (2019)

Galuminox: Preclinical validation of a novel PET tracer for non-invasive imaging of oxidative stress in vivo
por: Sivapackiam, Jothilingam, et al.
Publicado: (2020)

Prostate-Specific Antigen Screening and Recent Increases in Advanced Prostate Cancer
por: Nyame, Yaw A, et al.
Publicado: (2020)

Exceptional responses to PARP inhibitors in patients with metastatic breast cancer in oncologic crisis
por: Cheng, Joyce M., et al.
Publicado: (2023)

Prostate cancer and PARP inhibitors: progress and challenges
por: Teyssonneau, Diego, et al.
Publicado: (2021)

Radiosynthesis and Evaluation of Talazoparib and Its Derivatives as PARP-1-Targeting Agents
por: Zhou, Dong, et al.
Publicado: (2021)

Lipid Alterations in African American Men with Prostate Cancer
por: Ravindran, Anindita, et al.
Publicado: (2021)

An Animal Model with a Cardiomyocyte-Specific Deletion of Estrogen Receptor Alpha: Functional, Metabolic, and Differential Network Analysis
por: Devanathan, Sriram, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ka15t4s310bu5ga98pkn9v54me