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Cytarabine-Induced Bradycardia: A Case Report

Cardiotoxicity is damage to the heart muscle, which affects its function. Chemotherapy is known to cause cardiotoxicity along with many other medications and etiologies. Many chemotherapeutic cocktails are known to be associated with cardiotoxicities, such as taxane and cisplatin. Patients might hav...

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Detalles Bibliográficos
Autores principales: Albsheer, Khalid, Fadul, Abdalla, Khalafalla, Alaa, Abdalla, El Mustafa, Al-Dubai, Husam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681701/
https://www.ncbi.nlm.nih.gov/pubmed/36426323
http://dx.doi.org/10.7759/cureus.30624
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author Albsheer, Khalid
Fadul, Abdalla
Khalafalla, Alaa
Abdalla, El Mustafa
Al-Dubai, Husam
author_facet Albsheer, Khalid
Fadul, Abdalla
Khalafalla, Alaa
Abdalla, El Mustafa
Al-Dubai, Husam
author_sort Albsheer, Khalid
collection PubMed
description Cardiotoxicity is damage to the heart muscle, which affects its function. Chemotherapy is known to cause cardiotoxicity along with many other medications and etiologies. Many chemotherapeutic cocktails are known to be associated with cardiotoxicities, such as taxane and cisplatin. Patients might have arrhythmias, severe bradycardia, cardiomyopathy, and even cardiac arrest, so precautions are taken when such medications are started. This report presents a patient who developed severe symptomatic bradycardia after receiving idarubicin and cytarabine and was managed conservatively, along with a literature review of this entity.
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spelling pubmed-96817012022-11-23 Cytarabine-Induced Bradycardia: A Case Report Albsheer, Khalid Fadul, Abdalla Khalafalla, Alaa Abdalla, El Mustafa Al-Dubai, Husam Cureus Cardiology Cardiotoxicity is damage to the heart muscle, which affects its function. Chemotherapy is known to cause cardiotoxicity along with many other medications and etiologies. Many chemotherapeutic cocktails are known to be associated with cardiotoxicities, such as taxane and cisplatin. Patients might have arrhythmias, severe bradycardia, cardiomyopathy, and even cardiac arrest, so precautions are taken when such medications are started. This report presents a patient who developed severe symptomatic bradycardia after receiving idarubicin and cytarabine and was managed conservatively, along with a literature review of this entity. Cureus 2022-10-24 /pmc/articles/PMC9681701/ /pubmed/36426323 http://dx.doi.org/10.7759/cureus.30624 Text en Copyright © 2022, Albsheer et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Albsheer, Khalid
Fadul, Abdalla
Khalafalla, Alaa
Abdalla, El Mustafa
Al-Dubai, Husam
Cytarabine-Induced Bradycardia: A Case Report
title Cytarabine-Induced Bradycardia: A Case Report
title_full Cytarabine-Induced Bradycardia: A Case Report
title_fullStr Cytarabine-Induced Bradycardia: A Case Report
title_full_unstemmed Cytarabine-Induced Bradycardia: A Case Report
title_short Cytarabine-Induced Bradycardia: A Case Report
title_sort cytarabine-induced bradycardia: a case report
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681701/
https://www.ncbi.nlm.nih.gov/pubmed/36426323
http://dx.doi.org/10.7759/cureus.30624
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