Cargando…
DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs
The rational design of PROTACs is difficult due to their obscure structure-activity relationship. This study introduces a deep neural network model - DeepPROTACs to help design potent PROTACs molecules. It can predict the degradation capacity of a proposed PROTAC molecule based on structures of give...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681730/ https://www.ncbi.nlm.nih.gov/pubmed/36414666 http://dx.doi.org/10.1038/s41467-022-34807-3 |