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A rapid multiplex cell-free assay on biochip to evaluate functional aspects of double-strand break repair

The repair of DNA double-strand breaks (DSBs) involves interdependent molecular pathways, of which the choice is crucial for a cell’s fate when facing a damage. Growing evidence points toward the fact that DSB repair capacities correlate with disease aggressiveness, treatment response and treatment-...

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Detalles Bibliográficos
Autores principales: Tatin, Xavier, Muggiolu, Giovanna, Libert, Sarah, Béal, David, Maillet, Thierry, Breton, Jean, Sauvaigo, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681732/
https://www.ncbi.nlm.nih.gov/pubmed/36414637
http://dx.doi.org/10.1038/s41598-022-23819-0