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Human SERPINA3 induces neocortical folding and improves cognitive ability in mice

Neocortex expansion and folding are related to human intelligence and cognition, but the molecular and cellular mechanisms underlying cortical folding remain poorly understood. Here, we report that the human gene SERPINA3 is linked to gyrification. Specifically, the overexpression of SERPINA3 induce...

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Detalles Bibliográficos
Autores principales: Zhao, Jinyue, Feng, Chao, Wang, Wenwen, Su, Libo, Jiao, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681744/
https://www.ncbi.nlm.nih.gov/pubmed/36414636
http://dx.doi.org/10.1038/s41421-022-00469-0