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Human SERPINA3 induces neocortical folding and improves cognitive ability in mice
Neocortex expansion and folding are related to human intelligence and cognition, but the molecular and cellular mechanisms underlying cortical folding remain poorly understood. Here, we report that the human gene SERPINA3 is linked to gyrification. Specifically, the overexpression of SERPINA3 induce...
Autores principales: | Zhao, Jinyue, Feng, Chao, Wang, Wenwen, Su, Libo, Jiao, Jianwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681744/ https://www.ncbi.nlm.nih.gov/pubmed/36414636 http://dx.doi.org/10.1038/s41421-022-00469-0 |
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