dTMP imbalance through thymidylate 5′-phosphohydrolase activity induces apoptosis in triple-negative breast cancers

Immunotherapy has a number of advantages over traditional anti-tumor therapy but can cause severe adverse reactions due to an overactive immune system. In contrast, a novel metabolic treatment approach can induce metabolic vulnerability through multiple cancer cell targets. Here, we show a therapeut...

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Detalles Bibliográficos
Autores principales: Kim, Dae-Ho, Kim, Jin-Sook, Mok, Chang-Soo, Chang, En-Hyung, Choi, Jiwon, Lim, Junsub, Kim, Chul-Ho, Park, Ah-Reum, Bae, Yu-Jeong, Koo, Bong-Seong, Lee, Hyeon-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681768/
https://www.ncbi.nlm.nih.gov/pubmed/36414668
http://dx.doi.org/10.1038/s41598-022-24706-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681768/
https://www.ncbi.nlm.nih.gov/pubmed/36414668
http://dx.doi.org/10.1038/s41598-022-24706-4

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