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dTMP imbalance through thymidylate 5′-phosphohydrolase activity induces apoptosis in triple-negative breast cancers
Immunotherapy has a number of advantages over traditional anti-tumor therapy but can cause severe adverse reactions due to an overactive immune system. In contrast, a novel metabolic treatment approach can induce metabolic vulnerability through multiple cancer cell targets. Here, we show a therapeut...
Autores principales: | Kim, Dae-Ho, Kim, Jin-Sook, Mok, Chang-Soo, Chang, En-Hyung, Choi, Jiwon, Lim, Junsub, Kim, Chul-Ho, Park, Ah-Reum, Bae, Yu-Jeong, Koo, Bong-Seong, Lee, Hyeon-Cheol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681768/ https://www.ncbi.nlm.nih.gov/pubmed/36414668 http://dx.doi.org/10.1038/s41598-022-24706-4 |
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