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Directed evolution engineering to improve activity of glucose dehydrogenase by increasing pocket hydrophobicity
Glucose dehydrogenase (GDH) is a NAD(P)(+) dependent oxidoreductase, which is useful in glucose determination kits, glucose biosensors, cofactor regeneration, and biofuel cells. However, the low efficiency of the catalysis hinders the use of GDH in industrial applications. In this study, an analysis...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681798/ https://www.ncbi.nlm.nih.gov/pubmed/36439831 http://dx.doi.org/10.3389/fmicb.2022.1044226 |