Cargando…

Effects of Sophora flavescens aiton and the absorbed bioactive metabolite matrine individually and in combination with 5-fluorouracil on proliferation and apoptosis of gastric cancer cells in nude mice

Background: Sophora flavescens aiton (SFA) and its main bioactive metabolite matrine are widely used in traditional Chinese medicine (TCM) preparations and have achieved good curative effects for the treatment of various tumors. However, the mechanisms underlying SFA and matrine individually and in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Huan-Fu, Wang, Zheng, Tang, Wen-Li, Fu, Xue-Ming, Kong, Xiang-Jun, Qiu, Ying-Kun, Xi, Sheng-Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681822/ https://www.ncbi.nlm.nih.gov/pubmed/36438804 http://dx.doi.org/10.3389/fphar.2022.1047507

Ejemplares similares

Tissue culture and generation of autotetraploid plants of Sophora ﬂavescens Aiton
por: Kun-Hua, Wei, et al.
Publicado: (2010)

Production of Flavonoids in Callus Cultures of Sophora flavescens Aiton
por: Park, Ji-Sun, et al.
Publicado: (2020)

Sedative Effect of Sophora flavescens and Matrine
por: Lee, Hyun-ju, et al.
Publicado: (2017)

Profiling of the Major Phenolic Compounds and Their Biosynthesis Genes in Sophora flavescens Aiton
por: Lee, Jeongyeo, et al.
Publicado: (2018)

Construction of a “Bacteria-Metabolites” Co-Expression Network to Clarify the Anti–Ulcerative Colitis Effect of Flavonoids of Sophora flavescens Aiton by Regulating the “Host–Microbe” Interaction
por: Shao, Jing, et al.
Publicado: (2021)

Development of a Novel Electrochemical Sensor for Determination of Matrine in Sophora flavescens
por: Zhang, Junping, et al.
Publicado: (2017)

Sophora flavescens Aiton Decreases MPP(+)-Induced Mitochondrial Dysfunction in SH-SY5Y Cells
por: Kim, Hee-Young, et al.
Publicado: (2018)

Anti-Cervical Cancer Role of Matrine, Oxymatrine and Sophora Flavescens Alkaloid Gels and its Mechanism
por: Zhou, Yu Jie, et al.
Publicado: (2018)

Karyological, morphological and phytochemical characteristics of medicinal plants Sophora flavescens Aiton grown from seeds collected at different localities
por: Lin, Tzu Che, et al.
Publicado: (2014)

Anti-Tumor Activities of Bioactive Phytochemicals in Sophora flavescens for Breast Cancer
por: Cao, Xianjiao, et al.
Publicado: (2020)

Hepatotoxicity Induced by Sophora flavescens and Hepatic Accumulation of Kurarinone, a Major Hepatotoxic Constituent of Sophora flavescens in Rats
por: Jiang, Peng, et al.
Publicado: (2017)

Characterization of the complete chloroplast genome of shrubby sophora (Sophora flavescens Ait.)
por: Zhang, Wenlong, et al.
Publicado: (2018)

The Extract of Roots of Sophora flavescens Enhances the Recovery of Motor Function by Axonal Growth in Mice with a Spinal Cord Injury
por: Tanabe, Norio, et al.
Publicado: (2016)

Microwave-Assisted Extraction of Oxymatrine from Sophora flavescens
por: Xia, En-Qin, et al.
Publicado: (2011)

Optimization of Submerged Fermentation Medium for Matrine Production by Aspergillus terreus, an Endophytic Fungus Harboring Seeds of Sophora flavescens, Using Response Surface Methodology
por: Zhang, Qiang, et al.
Publicado: (2017)

Taxonomic Structure of Rhizosphere Bacterial Communities and Its Association With the Accumulation of Alkaloidal Metabolites in Sophora flavescens
por: Chen, Jie, et al.
Publicado: (2021)

Oxymatrine and its metabolite matrine contribute to the hepatotoxicity induced by radix Sophorae tonkinensis in mice
por: Gu, Yingmin, et al.
Publicado: (2019)

Selective Extraction of Flavonoids from Sophora flavescens Ait. by Mechanochemistry
por: Zhang, Qihong, et al.
Publicado: (2016)

Sex Difference of Effect of Sophora flavescens on Gut Microbiota in Rats
por: Duan, Xueqing, et al.
Publicado: (2022)

Chromosomal level genome assembly of medicinal plant Sophora flavescens
por: Qu, Zhipeng, et al.
Publicado: (2023)

Molecular mechanism of the anti-inflammatory effects of Sophorae Flavescentis Aiton identified by network pharmacology
por: Zhu, Naiqiang, et al.
Publicado: (2021)

Biosyntheses characterization of alkaloids and flavonoids in Sophora flavescens by combining metabolome and transcriptome
por: Wei, Guangfei, et al.
Publicado: (2021)

Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS
por: Dong, Yaqian, et al.
Publicado: (2021)

Oxidative Potential and Nanoantioxidant Activity of Flavonoids and Phenolic Acids in Sophora flavescens
por: Zhu, Yujie, et al.
Publicado: (2022)

Kushenol A and 8-prenylkaempferol, tyrosinase inhibitors, derived from Sophora flavescens
por: Kim, Jang Hoon, et al.
Publicado: (2018)

Two New Isoprenoid Flavonoids from Sophora flavescens with Antioxidant and Cytotoxic Activities
por: Li, Jingjing, et al.
Publicado: (2021)

Retracted: Oxidative Potential and Nanoantioxidant Activity of Flavonoids and Phenolic Acids in Sophora flavescens
por: Chemistry, International Journal of Analytical
Publicado: (2023)

Flavonoids from the Roots of Sophora flavescens and Their Potential Anti-Inflammatory and Antiproliferative Activities
por: Yang, Yan-Fei, et al.
Publicado: (2023)

Liquid chromatography-tandem mass spectrometry analysis of a ratio-optimized drug pair of Sophora flavescens Aiton and Coptis chinensis Franch and study on the mechanism of anti-colorectal cancer effect of two alkaloids thereof
por: Chen, Zihan, et al.
Publicado: (2023)

Anti-inflammatory effects of fermented and non-fermented Sophora flavescens: a comparative study
por: Han, Chun-chao, et al.
Publicado: (2011)

Characterization of the Plant Growth-Promoting Activities of Endophytic Fungi Isolated from Sophora flavescens
por: Turbat, Adiyadolgor, et al.
Publicado: (2020)

Diversity patterns of soil microbial communities in the Sophora flavescens rhizosphere in response to continuous monocropping
por: Lei, Haiying, et al.
Publicado: (2020)

Analysis of Genetic Diversity in the Traditional Chinese Medicine Plant ‘Kushen’ (Sophora flavescens Ait.)
por: Schultz, Carolyn J., et al.
Publicado: (2021)

Antimicrobial Effects of Sophora flavescens Alkaloids on Metronidazole-Resistant Gardnerella vaginalis in Planktonic and Biofilm Conditions
por: Fan, Linyuan, et al.
Publicado: (2023)

Synthesis of a Temperature-Sensitive Matrine-Imprinted Polymer and Its Potential Application for the Selective Extraction of Matrine from Radix Sophorae Tonkinensis
por: Jiang, Minjie, et al.
Publicado: (2015)

Linear Quantitative Profiling Method Fast Monitors Alkaloids of Sophora Flavescens That Was Verified by Tri-Marker Analyses
por: Hou, Zhifei, et al.
Publicado: (2016)

Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity
por: Kwon, Mincheol, et al.
Publicado: (2019)

The Synergistic Effect of Co-Treatment of Methyl Jasmonate and Cyclodextrins on Pterocarpan Production in Sophora flavescens Cell Cultures
por: Kim, Soyoung, et al.
Publicado: (2020)

Synthesis of hybrid carbon nanotube structures coated with Sophora flavescens nanoparticles and their application to antimicrobial air filtration
por: Hwang, Gi Byoung, et al.
Publicado: (2015)

In vitro anti-reovirus activity of kuraridin isolated from Sophora flavescens against viral replication and hemagglutination
por: Kwon, Hyung-Jun, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0pum973hdqd82h90i3vsvub94f