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Angiopoietin-like 2 is essential to aortic valve development in mice

Aortic valve (AoV) abnormalities during embryogenesis are a major risk for the development of aortic valve stenosis (AVS) and cardiac events later in life. Here, we identify an unexpected role for Angiopoietin-like 2 (ANGPTL2), a pro-inflammatory protein secreted by senescent cells, in valvulogenesi...

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Detalles Bibliográficos
Autores principales:	Labbé, Pauline, Munoz Goyette, Victoria, Thorin-Trescases, Nathalie, Villeneuve, Louis, Desanlis, Ines, Delwarde, Constance, Shi, Yan-Fen, Martel, Cécile, Yu, Carol, Alikashani, Azadeh, Mamarbachi, Maya, Lesage, Frédéric, Mathieu, Samuel, Tardif, Jean-Claude, Mathieu, Patrick, Kmita, Marie, Thorin, Éric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681843/ https://www.ncbi.nlm.nih.gov/pubmed/36414704 http://dx.doi.org/10.1038/s42003-022-04243-6

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