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Leukoreductive response to the combination of sorafenib and chemotherapy in hyperleukocytosis of FLT3-ITD mutated pediatric AML
Twelve to 22% of pediatric acute myeloid leukemia (AML) patients present with hyperleukocytosis, which is one of the main risk factors of early death due to its clinical complications: leukostasis, causing pulmonary or central nervous system injuries, tumor lysis syndrome, and disseminated intravasc...
Autores principales: | Schmidt, Franziska, Erlacher, Miriam, Niemeyer, Charlotte, Reinhardt, Dirk, Klusmann, Jan-Henning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681922/ https://www.ncbi.nlm.nih.gov/pubmed/36440328 http://dx.doi.org/10.3389/fped.2022.1046586 |
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