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Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management
Basal cell carcinoma (BCC) is the most common, accounting for 80–90% of skin cancers. It arises from the basal layer of the epidermis and its appendages. A complex interplay of environmental, phenotypic and genetic variables leads to the development of BCC. Literature has documented several clinical...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Healthcare
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681969/ https://www.ncbi.nlm.nih.gov/pubmed/35729457 http://dx.doi.org/10.1007/s40487-022-00201-8 |
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author | Naik, Piyu Parth Desai, Munaf B. |
author_facet | Naik, Piyu Parth Desai, Munaf B. |
author_sort | Naik, Piyu Parth |
collection | PubMed |
description | Basal cell carcinoma (BCC) is the most common, accounting for 80–90% of skin cancers. It arises from the basal layer of the epidermis and its appendages. A complex interplay of environmental, phenotypic and genetic variables leads to the development of BCC. Literature has documented several clinical subtypes of BCC, the most common of which are nodular, superficial and morpheaform. Expeditious diagnosis and analysis are essential for improving the outcome of BCC. Preventive measures, particularly when implemented in childhood and adolescence, may play a critical role. Due to its low metastatic potential, treatment for BCC mostly focuses on local management. The standard treatment of basal cell carcinoma involved complete removal of the lesion by excision or Mohs surgery. In special circumstances, basal cell carcinoma can be treated with cryosurgery, electrodesiccation and curettage, topical medications and photodynamic therapy. This review aimed to evaluate the contemporary diagnosis and management of basal cell carcinoma. |
format | Online Article Text |
id | pubmed-9681969 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-96819692022-11-24 Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management Naik, Piyu Parth Desai, Munaf B. Oncol Ther Review Basal cell carcinoma (BCC) is the most common, accounting for 80–90% of skin cancers. It arises from the basal layer of the epidermis and its appendages. A complex interplay of environmental, phenotypic and genetic variables leads to the development of BCC. Literature has documented several clinical subtypes of BCC, the most common of which are nodular, superficial and morpheaform. Expeditious diagnosis and analysis are essential for improving the outcome of BCC. Preventive measures, particularly when implemented in childhood and adolescence, may play a critical role. Due to its low metastatic potential, treatment for BCC mostly focuses on local management. The standard treatment of basal cell carcinoma involved complete removal of the lesion by excision or Mohs surgery. In special circumstances, basal cell carcinoma can be treated with cryosurgery, electrodesiccation and curettage, topical medications and photodynamic therapy. This review aimed to evaluate the contemporary diagnosis and management of basal cell carcinoma. Springer Healthcare 2022-06-21 /pmc/articles/PMC9681969/ /pubmed/35729457 http://dx.doi.org/10.1007/s40487-022-00201-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Review Naik, Piyu Parth Desai, Munaf B. Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management |
title | Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management |
title_full | Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management |
title_fullStr | Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management |
title_full_unstemmed | Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management |
title_short | Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management |
title_sort | basal cell carcinoma: a narrative review on contemporary diagnosis and management |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681969/ https://www.ncbi.nlm.nih.gov/pubmed/35729457 http://dx.doi.org/10.1007/s40487-022-00201-8 |
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