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Tumor and microenvironmental mechanisms of resistance to immunomodulatory drugs in multiple myeloma
Resistance to immunomodulatory drugs (IMiDs(®)) is a major cause of treatment failure, disease relapse and ultimately poorer outcomes in multiple myeloma (MM). In order to optimally deploy IMiDs and their newer derivates CRBN E3 ligase modulators (CELMoDs(®)) into future myeloma therapeutic regimens...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682014/ https://www.ncbi.nlm.nih.gov/pubmed/36439455 http://dx.doi.org/10.3389/fonc.2022.1038329 |