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Impact of COVID-19 on Nonpulmonary Critical Illness: Prevalence, Clinical Manifestations, Management, and Outcomes

Although respiratory manifestations are the most common driver of hospitalization, SARS-CoV-2 infection has a wide range of manifestations, including multisystem organ failure in severe cases. This review discusses the prevalence, pathophysiology, clinical manifestations, treatment, and outcomes of...

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Detalles Bibliográficos
Autores principales: Pirzadeh, Mina, Prescott, Hallie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Health Sciences Division 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682059/
https://www.ncbi.nlm.nih.gov/pubmed/37085218
http://dx.doi.org/10.1016/j.ccm.2022.11.011
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author Pirzadeh, Mina
Prescott, Hallie C.
author_facet Pirzadeh, Mina
Prescott, Hallie C.
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description Although respiratory manifestations are the most common driver of hospitalization, SARS-CoV-2 infection has a wide range of manifestations, including multisystem organ failure in severe cases. This review discusses the prevalence, pathophysiology, clinical manifestations, treatment, and outcomes of nonpulmonary organ dysfunction from SARS-CoV2, including renal, liver, cardiac, neurologic, and coagulation system dysfunction. At this time, management largely focuses on supportive care practices that are applicable regardless of the cause of organ injury.
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spelling pubmed-96820592022-11-23 Impact of COVID-19 on Nonpulmonary Critical Illness: Prevalence, Clinical Manifestations, Management, and Outcomes Pirzadeh, Mina Prescott, Hallie C. Clin Chest Med Article Although respiratory manifestations are the most common driver of hospitalization, SARS-CoV-2 infection has a wide range of manifestations, including multisystem organ failure in severe cases. This review discusses the prevalence, pathophysiology, clinical manifestations, treatment, and outcomes of nonpulmonary organ dysfunction from SARS-CoV2, including renal, liver, cardiac, neurologic, and coagulation system dysfunction. At this time, management largely focuses on supportive care practices that are applicable regardless of the cause of organ injury. Elsevier Health Sciences Division 2023-06 2022-11-23 /pmc/articles/PMC9682059/ /pubmed/37085218 http://dx.doi.org/10.1016/j.ccm.2022.11.011 Text en Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Pirzadeh, Mina
Prescott, Hallie C.
Impact of COVID-19 on Nonpulmonary Critical Illness: Prevalence, Clinical Manifestations, Management, and Outcomes
title Impact of COVID-19 on Nonpulmonary Critical Illness: Prevalence, Clinical Manifestations, Management, and Outcomes
title_full Impact of COVID-19 on Nonpulmonary Critical Illness: Prevalence, Clinical Manifestations, Management, and Outcomes
title_fullStr Impact of COVID-19 on Nonpulmonary Critical Illness: Prevalence, Clinical Manifestations, Management, and Outcomes
title_full_unstemmed Impact of COVID-19 on Nonpulmonary Critical Illness: Prevalence, Clinical Manifestations, Management, and Outcomes
title_short Impact of COVID-19 on Nonpulmonary Critical Illness: Prevalence, Clinical Manifestations, Management, and Outcomes
title_sort impact of covid-19 on nonpulmonary critical illness: prevalence, clinical manifestations, management, and outcomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682059/
https://www.ncbi.nlm.nih.gov/pubmed/37085218
http://dx.doi.org/10.1016/j.ccm.2022.11.011
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