Granzyme B in circulating CD8+ T cells as a biomarker of immunotherapy effectiveness and disability in neuromyelitis optica spectrum disorders

BACKGROUND AND OBJECTIVE: Neuromyelitis optica spectrum disorders (NMOSD) are chronical inflammatory demyelinating diseases of the central nervous system (CNS) and the underlying mechanism remains unclear. Several recent studies have demonstrated that T cells play a pivotal role in the pathogenesis...

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Detalles Bibliográficos
Autores principales: Shi, Ziyan, Du, Qin, Wang, Xiaofei, Wang, Jianchen, Chen, Hongxi, Lang, Yanling, Kong, Lingyao, Luo, Wenqin, Yang, Mu, Zhou, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682179/
https://www.ncbi.nlm.nih.gov/pubmed/36439094
http://dx.doi.org/10.3389/fimmu.2022.1027158

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