Cargando…

Identification of six hub genes and two key pathways in two rat renal fibrosis models based on bioinformatics and RNA-seq transcriptome analyses

Renal fibrosis (RF) is the common pathological manifestation and central treatment target of multiple chronic kidney diseases with high morbidity and mortality. Currently, the molecular mechanisms underlying RF remain poorly understood, and exploration of RF-related hub targets and pathways is urgen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Yueqin, Chen, Jingan, Liu, Jingyan, Zhu, Keyan, Xu, Zhixing, Shen, Jianan, Wang, Dejun, Chu, Lisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682235/ https://www.ncbi.nlm.nih.gov/pubmed/36438657 http://dx.doi.org/10.3389/fmolb.2022.1035772

Ejemplares similares

Identification of Hub Genes and Pathways Associated With Idiopathic Pulmonary Fibrosis via Bioinformatics Analysis
por: Wan, Hanxi, et al.
Publicado: (2021)

Identification of the hub and prognostic genes in liver hepatocellular carcinoma via bioinformatics analysis
por: Gao, Qiannan, et al.
Publicado: (2022)

Identification of Crucial Hub Genes and Differential T Cell Infiltration in Idiopathic Pulmonary Arterial Hypertension Using Bioinformatics Strategies
por: Yang, Xiaomei, et al.
Publicado: (2022)

Bioinformatic Analysis Combined With Experimental Validation Reveals Novel Hub Genes and Pathways Associated With Focal Segmental Glomerulosclerosis
por: Hou, Yan-Pei, et al.
Publicado: (2022)

Identification of hub genes and immune cell infiltration characteristics in chronic rhinosinusitis with nasal polyps: Bioinformatics analysis and experimental validation
por: Pan, Yangwang, et al.
Publicado: (2022)

Bioinformatic Analyses of the Ferroptosis-Related lncRNAs Signature for Ovarian Cancer
por: Zheng, Jianfeng, et al.
Publicado: (2022)

Potential Role of NEU1 in Hepatocellular Carcinoma: A Study Based on Comprehensive Bioinformatical Analysis
por: Wu, Zhulin, et al.
Publicado: (2021)

Bioinformatic Analyses of Canonical Pathways of TSPOAP1 and its Roles in Human Diseases
por: Suthar, Sharad Kumar, et al.
Publicado: (2021)

Identification of Key Biomarkers and Immune Infiltration in Systemic Juvenile Idiopathic Arthritis by Integrated Bioinformatic Analysis
por: Zhang, Min, et al.
Publicado: (2021)

Identification of PTK2 as an adverse prognostic biomarker in breast cancer by integrated bioinformatics and experimental analyses
por: Chen, Yanru, et al.
Publicado: (2022)

Identification of Potential Ferroptosis Key Genes in the Pathogenesis of Lumbosacral Spinal Root Avulsion by RNA Sequencing and Bioinformatics Analysis
por: Zhou, Zhibin, et al.
Publicado: (2022)

Identification of key signaling pathways and hub genes related to immune infiltration in Kawasaki disease with resistance to intravenous immunoglobulin based on weighted gene co-expression network analysis
por: Wang, Yue, et al.
Publicado: (2023)

Identification and Validation of Prognostic Biomarkers Specifically Expressed in Macrophage in IgA Nephropathy Patients Based on Integrated Bioinformatics Analyses
por: Ding, Yuqing, et al.
Publicado: (2022)

Identification of AKR1B10 as a key gene in primary biliary cholangitis by integrated bioinformatics analysis and experimental validation
por: Wang, Huiwen, et al.
Publicado: (2023)

Identification of Four Novel Prognostic Biomarkers and Construction of Two Nomograms in Adrenocortical Carcinoma: A Multi-Omics Data Study via Bioinformatics and Machine Learning Methods
por: Yi, Xiaochun, et al.
Publicado: (2022)

Bioinformatic Analyses and Experimental Verification Reveal that High FSTL3 Expression Promotes EMT via Fibronectin-1/α5β1 Interaction in Colorectal Cancer
por: Liu, Yuanjie, et al.
Publicado: (2021)

The cytosolic N-terminal domain of V-ATPase a-subunits is a regulatory hub targeted by multiple signals
por: Tuli, Farzana, et al.
Publicado: (2023)

Six-Month Outcomes of Post-ARDS Pulmonary Fibrosis in Patients With H1N1 Pneumonia
por: Gao, Jing, et al.
Publicado: (2021)

Identification of hub genes regulating the cell activity and function of adipose-derived stem cells under oxygen-glucose deprivation
por: Yang, Zhenyu, et al.
Publicado: (2022)

Hub Long Noncoding RNAs with m6A Modification for Signatures and Prognostic Values in Kidney Renal Clear Cell Carcinoma
por: Lin, Gaoteng, et al.
Publicado: (2021)

Two-dimensional measurements of receptor-ligand interactions
por: Zheng, Songjie, et al.
Publicado: (2023)

Agonist Binding to Chemosensory Receptors: A Systematic Bioinformatics Analysis
por: Fierro, Fabrizio, et al.
Publicado: (2017)

Bioinformatics and Biosimulations as Toolbox for Peptides and Peptidomimetics Design: Where Are We?
por: D’Annessa, Ilda, et al.
Publicado: (2020)

The World of Stable Ribonucleoproteins and Its Mapping With Grad-Seq and Related Approaches
por: Gerovac, Milan, et al.
Publicado: (2021)

Comprehensive bioinformatics and machine learning analysis identify VCAN as a novel biomarker of hepatitis B virus-related liver fibrosis
por: Yuan, Mengqin, et al.
Publicado: (2022)

Identification and Validation of a Novel Three Hub Long Noncoding RNAs With m6A Modification Signature in Low-Grade Gliomas
por: Nguyen, Quang-Huy, et al.
Publicado: (2022)

Drug Resistance in Glioblastoma: The Two Faces of Oxidative Stress
por: Olivier, Christophe, et al.
Publicado: (2021)

Integrative bioinformatics analysis to identify the effects of circadian rhythm on Crohn’s disease
por: Liu, Dan, et al.
Publicado: (2022)

Targeted Analysis of circRNA Expression in Patient Samples by Lexo-circSeq
por: Naarmann-de Vries, Isabel S., et al.
Publicado: (2022)

Comparing Two Neurodevelopmental Disorders Linked to CK2: Okur-Chung Neurodevelopmental Syndrome and Poirier-Bienvenu Neurodevelopmental Syndrome—Two Sides of the Same Coin?
por: Ballardin, Demetra, et al.
Publicado: (2022)

TRAF2 as a key candidate gene in clinical hepatitis B-associated liver fibrosis
por: Wu, Cichun, et al.
Publicado: (2023)

Insight into Two ABC Transporter Families Involved in Lantibiotic Resistance
por: Clemens, Rebecca, et al.
Publicado: (2018)

Optimal Experimental Design Based on Two-Dimensional Likelihood Profiles
por: Litwin, Tim, et al.
Publicado: (2022)

Supported Lipid Bilayers and the Study of Two-Dimensional Binding Kinetics
por: Dam, Tommy, et al.
Publicado: (2022)

Untargeted metabolomics of the cochleae from two laryngeally echolocating bats
por: Wang, Hui, et al.
Publicado: (2023)

Right in two: capabilities of ion mobility spectrometry for untargeted metabolomics
por: Moses, Tessa, et al.
Publicado: (2023)

Identification of Radiotherapy-Associated Genes in Lung Adenocarcinoma by an Integrated Bioinformatics Analysis Approach
por: Wang, Junhao, et al.
Publicado: (2021)

Screening of ferroptosis-related genes with prognostic effect in colorectal cancer by bioinformatic analysis
por: Hu, Dongzhi, et al.
Publicado: (2022)

Proteomics and bioinformatics analysis of follicular fluid from patients with polycystic ovary syndrome
por: Wang, Wenqi, et al.
Publicado: (2022)

Detection of Alu Exonization Events in Human Frontal Cortex From RNA-Seq Data
por: Florea, Liliana, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7ckk62v6qmvi3n4k0sfbeomopq